Photopheresis Provides Significant Long-Lasting Benefit in Nephrogenic Systemic Fibrosis

Nephrogenic systemic fibrosis (NSF), previously known as nephrogenic fibrosing dermopathy, is a rare complication of exposure to gadolinium-based contrast agents in patients who have significantly decreased renal function. Manifestations include fibrosis of the skin and other tissues. Effective ther...

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Main Authors: Ranran Zhang, William Nicholas Rose
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2017/3240287
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author Ranran Zhang
William Nicholas Rose
author_facet Ranran Zhang
William Nicholas Rose
author_sort Ranran Zhang
collection DOAJ
description Nephrogenic systemic fibrosis (NSF), previously known as nephrogenic fibrosing dermopathy, is a rare complication of exposure to gadolinium-based contrast agents in patients who have significantly decreased renal function. Manifestations include fibrosis of the skin and other tissues. Effective therapies are lacking. Photopheresis has been tried with variable rates of improvement, and small numbers of cases (20 as of 2016) have been reported of NSF patients treated with photopheresis. We report a case of patient with nephrogenic systemic fibrosis who was treated with photopheresis and demonstrated significant lasting improvements.
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institution Kabale University
issn 2090-6463
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language English
publishDate 2017-01-01
publisher Wiley
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series Case Reports in Dermatological Medicine
spelling doaj-art-1211ba18473d44c9a49d8430ef16f9162025-02-03T01:01:47ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712017-01-01201710.1155/2017/32402873240287Photopheresis Provides Significant Long-Lasting Benefit in Nephrogenic Systemic FibrosisRanran Zhang0William Nicholas Rose1Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI, USADepartment of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI, USANephrogenic systemic fibrosis (NSF), previously known as nephrogenic fibrosing dermopathy, is a rare complication of exposure to gadolinium-based contrast agents in patients who have significantly decreased renal function. Manifestations include fibrosis of the skin and other tissues. Effective therapies are lacking. Photopheresis has been tried with variable rates of improvement, and small numbers of cases (20 as of 2016) have been reported of NSF patients treated with photopheresis. We report a case of patient with nephrogenic systemic fibrosis who was treated with photopheresis and demonstrated significant lasting improvements.http://dx.doi.org/10.1155/2017/3240287
spellingShingle Ranran Zhang
William Nicholas Rose
Photopheresis Provides Significant Long-Lasting Benefit in Nephrogenic Systemic Fibrosis
Case Reports in Dermatological Medicine
title Photopheresis Provides Significant Long-Lasting Benefit in Nephrogenic Systemic Fibrosis
title_full Photopheresis Provides Significant Long-Lasting Benefit in Nephrogenic Systemic Fibrosis
title_fullStr Photopheresis Provides Significant Long-Lasting Benefit in Nephrogenic Systemic Fibrosis
title_full_unstemmed Photopheresis Provides Significant Long-Lasting Benefit in Nephrogenic Systemic Fibrosis
title_short Photopheresis Provides Significant Long-Lasting Benefit in Nephrogenic Systemic Fibrosis
title_sort photopheresis provides significant long lasting benefit in nephrogenic systemic fibrosis
url http://dx.doi.org/10.1155/2017/3240287
work_keys_str_mv AT ranranzhang photopheresisprovidessignificantlonglastingbenefitinnephrogenicsystemicfibrosis
AT williamnicholasrose photopheresisprovidessignificantlonglastingbenefitinnephrogenicsystemicfibrosis