UV Spectrophotometric Method for Determination of Cinitapride in Pure and its Solid Dosage Form
A new, rapid, precise, accurate and sensitive analytical method was developed for the UV spectrophotometric assay of cinitapride (CTP). The drug obeyed the Beer's law and showed good correlation. It showed absorption maxima at 260 nm in methanol. The linearity was observed between 5-40 µg mL-1....
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2009/856537 |
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| author | B. Thangabalan A. Elphine Prabahar R. Kalaichelvi P. Vijayaraj Kumar |
| author_facet | B. Thangabalan A. Elphine Prabahar R. Kalaichelvi P. Vijayaraj Kumar |
| author_sort | B. Thangabalan |
| collection | DOAJ |
| description | A new, rapid, precise, accurate and sensitive analytical method was developed for the UV spectrophotometric assay of cinitapride (CTP). The drug obeyed the Beer's law and showed good correlation. It showed absorption maxima at 260 nm in methanol. The linearity was observed between 5-40 µg mL-1. The results of analysis were validated by recovery studies. The recovery was more than 99%. The proposed method is the only method available for spectrophotometric determination of the drug. It is simple, precise, sensitive and reproducible and can be used for the routine quality control testing of the marketed formulations. |
| format | Article |
| id | doaj-art-11f17c019439488488e2a1e462ac0d30 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-11f17c019439488488e2a1e462ac0d302025-02-03T06:07:24ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-016S1S21S2410.1155/2009/856537UV Spectrophotometric Method for Determination of Cinitapride in Pure and its Solid Dosage FormB. Thangabalan0A. Elphine Prabahar1R. Kalaichelvi2P. Vijayaraj Kumar3SIMS College of Pharmacy, Mangaladas Nagar, Guntur-522 001, IndiaDepartment of Pharmacy, Donbosco PG College, Vatticherukuru Mandal, Guntur-522 017, IndiaK.C.Reddy Institute of Pharmaceutical Sciences, Jangamguntla Palem, Medikonduru Mandal, Guntur-522 348, IndiaBuharat Institute Pharmacy, Mangapally Village, Ibrahimpatnam , RR Dist-501 506, IndiaA new, rapid, precise, accurate and sensitive analytical method was developed for the UV spectrophotometric assay of cinitapride (CTP). The drug obeyed the Beer's law and showed good correlation. It showed absorption maxima at 260 nm in methanol. The linearity was observed between 5-40 µg mL-1. The results of analysis were validated by recovery studies. The recovery was more than 99%. The proposed method is the only method available for spectrophotometric determination of the drug. It is simple, precise, sensitive and reproducible and can be used for the routine quality control testing of the marketed formulations.http://dx.doi.org/10.1155/2009/856537 |
| spellingShingle | B. Thangabalan A. Elphine Prabahar R. Kalaichelvi P. Vijayaraj Kumar UV Spectrophotometric Method for Determination of Cinitapride in Pure and its Solid Dosage Form E-Journal of Chemistry |
| title | UV Spectrophotometric Method for Determination of Cinitapride in Pure and its Solid Dosage Form |
| title_full | UV Spectrophotometric Method for Determination of Cinitapride in Pure and its Solid Dosage Form |
| title_fullStr | UV Spectrophotometric Method for Determination of Cinitapride in Pure and its Solid Dosage Form |
| title_full_unstemmed | UV Spectrophotometric Method for Determination of Cinitapride in Pure and its Solid Dosage Form |
| title_short | UV Spectrophotometric Method for Determination of Cinitapride in Pure and its Solid Dosage Form |
| title_sort | uv spectrophotometric method for determination of cinitapride in pure and its solid dosage form |
| url | http://dx.doi.org/10.1155/2009/856537 |
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