A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer
Abstract Few studies have investigated quality of life (QoL) improvements in patients with colorectal cancer or the benefits of digital healthcare interventions. This randomized controlled trial assessed the impact of mobile applications on postoperative QoL in patients scheduled for curative surger...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-05-01
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| Series: | npj Digital Medicine |
| Online Access: | https://doi.org/10.1038/s41746-025-01716-w |
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| author | Young Il Kim In Ja Park Jun-Soo Ro Jong Lyul Lee Chan Wook Kim Yong Sik Yoon Seok-Byung Lim Chang Sik Yu Yura Lee Yae Won Tak Seockhoon Chung Kyung Won Kim Yousun Ko Sung-Cheol Yun Min-Woo Jo Jong Won Lee |
| author_facet | Young Il Kim In Ja Park Jun-Soo Ro Jong Lyul Lee Chan Wook Kim Yong Sik Yoon Seok-Byung Lim Chang Sik Yu Yura Lee Yae Won Tak Seockhoon Chung Kyung Won Kim Yousun Ko Sung-Cheol Yun Min-Woo Jo Jong Won Lee |
| author_sort | Young Il Kim |
| collection | DOAJ |
| description | Abstract Few studies have investigated quality of life (QoL) improvements in patients with colorectal cancer or the benefits of digital healthcare interventions. This randomized controlled trial assessed the impact of mobile applications on postoperative QoL in patients scheduled for curative surgery for colorectal cancer. Patients were randomized into three intervention groups (each using a different mobile application for postoperative lifestyle management) and a control group. QoL was evaluated using the European Quality of Life-5 Dimensions (EQ-5D), with physical and metabolic parameters and fat/muscle areas measured preoperatively, and every six months postoperatively. At six months, no significant differences in the EQ-5D scores from baseline were observed across groups. Intervention Group C showed a significant increase in skeletal muscle area compared to the control group (P = 0.046). Overall, mobile application use had a minimal effect on postoperative health-related QoL, warranting further research on their efficacy and compliance rates. Trial registration: CRIS.nih.go.kr: KCT0005447. Registration date: June 23, 2020. |
| format | Article |
| id | doaj-art-11ec9ef4cb704517b77a5249cce19aa2 |
| institution | Kabale University |
| issn | 2398-6352 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Digital Medicine |
| spelling | doaj-art-11ec9ef4cb704517b77a5249cce19aa22025-08-20T03:47:16ZengNature Portfolionpj Digital Medicine2398-63522025-05-01811910.1038/s41746-025-01716-wA randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancerYoung Il Kim0In Ja Park1Jun-Soo Ro2Jong Lyul Lee3Chan Wook Kim4Yong Sik Yoon5Seok-Byung Lim6Chang Sik Yu7Yura Lee8Yae Won Tak9Seockhoon Chung10Kyung Won Kim11Yousun Ko12Sung-Cheol Yun13Min-Woo Jo14Jong Won Lee15Division of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of MedicineDivision of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of MedicineDepartment of Preventive Medicine & Public Health, Ajou University School of MedicineDivision of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of MedicineDivision of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of MedicineDivision of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of MedicineDivision of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of MedicineDivision of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of MedicineDepartment of Information Medicine, Asan Medical Center, University of Ulsan College of MedicineDepartment of Information Medicine, Asan Medical Center, University of Ulsan College of MedicineDepartment of Psychiatry, Asan Medical Center, University of Ulsan College of MedicineDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of MedicineBiomedical Research Center, Asan Institute for Life Sciences, Asan Medical CenterDivision of Epidemiology and Biostatics, Clinical Research Center, Asan Medical CenterDepartment of Preventive Medicine, University of Ulsan College of MedicineDivision of Breast Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of MedicineAbstract Few studies have investigated quality of life (QoL) improvements in patients with colorectal cancer or the benefits of digital healthcare interventions. This randomized controlled trial assessed the impact of mobile applications on postoperative QoL in patients scheduled for curative surgery for colorectal cancer. Patients were randomized into three intervention groups (each using a different mobile application for postoperative lifestyle management) and a control group. QoL was evaluated using the European Quality of Life-5 Dimensions (EQ-5D), with physical and metabolic parameters and fat/muscle areas measured preoperatively, and every six months postoperatively. At six months, no significant differences in the EQ-5D scores from baseline were observed across groups. Intervention Group C showed a significant increase in skeletal muscle area compared to the control group (P = 0.046). Overall, mobile application use had a minimal effect on postoperative health-related QoL, warranting further research on their efficacy and compliance rates. Trial registration: CRIS.nih.go.kr: KCT0005447. Registration date: June 23, 2020.https://doi.org/10.1038/s41746-025-01716-w |
| spellingShingle | Young Il Kim In Ja Park Jun-Soo Ro Jong Lyul Lee Chan Wook Kim Yong Sik Yoon Seok-Byung Lim Chang Sik Yu Yura Lee Yae Won Tak Seockhoon Chung Kyung Won Kim Yousun Ko Sung-Cheol Yun Min-Woo Jo Jong Won Lee A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer npj Digital Medicine |
| title | A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer |
| title_full | A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer |
| title_fullStr | A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer |
| title_full_unstemmed | A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer |
| title_short | A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer |
| title_sort | randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer |
| url | https://doi.org/10.1038/s41746-025-01716-w |
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