New progress in imaging diagnosis and immunotherapy of breast cancer
Breast cancer (BC) is a predominant malignancy among women globally, with its etiology remaining largely elusive. Diagnosis primarily relies on invasive histopathological methods, which are often limited by sample representation and processing time. Consequently, non-invasive imaging techniques such...
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Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1560257/full |
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| author | Jie He Nan Liu Li Zhao |
| author_facet | Jie He Nan Liu Li Zhao |
| author_sort | Jie He |
| collection | DOAJ |
| description | Breast cancer (BC) is a predominant malignancy among women globally, with its etiology remaining largely elusive. Diagnosis primarily relies on invasive histopathological methods, which are often limited by sample representation and processing time. Consequently, non-invasive imaging techniques such as mammography, ultrasound, and Magnetic Resonance Imaging (MRI) are indispensable for BC screening, diagnosis, staging, and treatment monitoring. Recent advancements in imaging technologies and artificial intelligence-driven radiomics have enhanced precision medicine by enabling early detection, accurate molecular subtyping, and personalized therapeutic strategies. Despite reductions in mortality through traditional treatments, challenges like tumor heterogeneity and therapeutic resistance persist. Immunotherapies, particularly PD-1/PD-L1 inhibitors, have emerged as promising alternatives. This review explores recent developments in BC imaging diagnostics and immunotherapeutic approaches, aiming to inform clinical practices and optimize therapeutic outcomes. |
| format | Article |
| id | doaj-art-11e00007680c49e497ae0c839bc2234f |
| institution | DOAJ |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-11e00007680c49e497ae0c839bc2234f2025-08-20T02:56:02ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-03-011610.3389/fimmu.2025.15602571560257New progress in imaging diagnosis and immunotherapy of breast cancerJie He0Nan Liu1Li Zhao2Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, ChinaDepartment of Translational Medicine and Clinical Research, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, ChinaDepartment of Radiology, Shaoxing People’s Hospital, Shaoxing, Zhejiang, ChinaBreast cancer (BC) is a predominant malignancy among women globally, with its etiology remaining largely elusive. Diagnosis primarily relies on invasive histopathological methods, which are often limited by sample representation and processing time. Consequently, non-invasive imaging techniques such as mammography, ultrasound, and Magnetic Resonance Imaging (MRI) are indispensable for BC screening, diagnosis, staging, and treatment monitoring. Recent advancements in imaging technologies and artificial intelligence-driven radiomics have enhanced precision medicine by enabling early detection, accurate molecular subtyping, and personalized therapeutic strategies. Despite reductions in mortality through traditional treatments, challenges like tumor heterogeneity and therapeutic resistance persist. Immunotherapies, particularly PD-1/PD-L1 inhibitors, have emerged as promising alternatives. This review explores recent developments in BC imaging diagnostics and immunotherapeutic approaches, aiming to inform clinical practices and optimize therapeutic outcomes.https://www.frontiersin.org/articles/10.3389/fimmu.2025.1560257/fullbreast cancerPD-1immune checkpointimmunotherapyradiotherapyimaging diagnosis |
| spellingShingle | Jie He Nan Liu Li Zhao New progress in imaging diagnosis and immunotherapy of breast cancer Frontiers in Immunology breast cancer PD-1 immune checkpoint immunotherapy radiotherapy imaging diagnosis |
| title | New progress in imaging diagnosis and immunotherapy of breast cancer |
| title_full | New progress in imaging diagnosis and immunotherapy of breast cancer |
| title_fullStr | New progress in imaging diagnosis and immunotherapy of breast cancer |
| title_full_unstemmed | New progress in imaging diagnosis and immunotherapy of breast cancer |
| title_short | New progress in imaging diagnosis and immunotherapy of breast cancer |
| title_sort | new progress in imaging diagnosis and immunotherapy of breast cancer |
| topic | breast cancer PD-1 immune checkpoint immunotherapy radiotherapy imaging diagnosis |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1560257/full |
| work_keys_str_mv | AT jiehe newprogressinimagingdiagnosisandimmunotherapyofbreastcancer AT nanliu newprogressinimagingdiagnosisandimmunotherapyofbreastcancer AT lizhao newprogressinimagingdiagnosisandimmunotherapyofbreastcancer |