Role of Peritoneal Macrophages in Cytomegalovirus-induced Acceleration of Autoimmune Diabetes in BB-rats

Background: As one of the natural perturbants, infection with cytomegalovirus (CMV) is believed to play a role in the development of Type I diabetes. Using the DP-BB rat model for autoimmune diabetes, we here report about possible mechanisms responsible for R(at)CMV-induced accelerated onset of diab...

Full description

Saved in:
Bibliographic Details
Main Authors: Jan-Luuk Hillebrands, Nienke van der Werf, Flip A. Klatter, Cathrien A. Bruggeman, Jan Rozing
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1080/10446670310001626517
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850236856762892288
author Jan-Luuk Hillebrands
Nienke van der Werf
Flip A. Klatter
Cathrien A. Bruggeman
Jan Rozing
author_facet Jan-Luuk Hillebrands
Nienke van der Werf
Flip A. Klatter
Cathrien A. Bruggeman
Jan Rozing
author_sort Jan-Luuk Hillebrands
collection DOAJ
description Background: As one of the natural perturbants, infection with cytomegalovirus (CMV) is believed to play a role in the development of Type I diabetes. Using the DP-BB rat model for autoimmune diabetes, we here report about possible mechanisms responsible for R(at)CMV-induced accelerated onset of diabetes.
format Article
id doaj-art-11dfcfa2ecf04616b821b105cce0b1ee
institution OA Journals
issn 1740-2522
1740-2530
language English
publishDate 2003-01-01
publisher Wiley
record_format Article
series Clinical and Developmental Immunology
spelling doaj-art-11dfcfa2ecf04616b821b105cce0b1ee2025-08-20T02:01:53ZengWileyClinical and Developmental Immunology1740-25221740-25302003-01-01102-413313910.1080/10446670310001626517Role of Peritoneal Macrophages in Cytomegalovirus-induced Acceleration of Autoimmune Diabetes in BB-ratsJan-Luuk Hillebrands0Nienke van der Werf1Flip A. Klatter2Cathrien A. Bruggeman3Jan Rozing4Faculty of Medical Sciences, Immunology Section, Department of Cell Biology, University of Groningen, A. Deusinglaan 1, Groningen NL-9713 AV, The NetherlandsFaculty of Medical Sciences, Immunology Section, Department of Cell Biology, University of Groningen, A. Deusinglaan 1, Groningen NL-9713 AV, The NetherlandsFaculty of Medical Sciences, Immunology Section, Department of Cell Biology, University of Groningen, A. Deusinglaan 1, Groningen NL-9713 AV, The NetherlandsDepartment of Medical Microbiology, University Hospital Maastricht, P. Deleyelaan 25, Maastricht NL-6202 AZ, The NetherlandsFaculty of Medical Sciences, Immunology Section, Department of Cell Biology, University of Groningen, A. Deusinglaan 1, Groningen NL-9713 AV, The NetherlandsBackground: As one of the natural perturbants, infection with cytomegalovirus (CMV) is believed to play a role in the development of Type I diabetes. Using the DP-BB rat model for autoimmune diabetes, we here report about possible mechanisms responsible for R(at)CMV-induced accelerated onset of diabetes.http://dx.doi.org/10.1080/10446670310001626517
spellingShingle Jan-Luuk Hillebrands
Nienke van der Werf
Flip A. Klatter
Cathrien A. Bruggeman
Jan Rozing
Role of Peritoneal Macrophages in Cytomegalovirus-induced Acceleration of Autoimmune Diabetes in BB-rats
Clinical and Developmental Immunology
title Role of Peritoneal Macrophages in Cytomegalovirus-induced Acceleration of Autoimmune Diabetes in BB-rats
title_full Role of Peritoneal Macrophages in Cytomegalovirus-induced Acceleration of Autoimmune Diabetes in BB-rats
title_fullStr Role of Peritoneal Macrophages in Cytomegalovirus-induced Acceleration of Autoimmune Diabetes in BB-rats
title_full_unstemmed Role of Peritoneal Macrophages in Cytomegalovirus-induced Acceleration of Autoimmune Diabetes in BB-rats
title_short Role of Peritoneal Macrophages in Cytomegalovirus-induced Acceleration of Autoimmune Diabetes in BB-rats
title_sort role of peritoneal macrophages in cytomegalovirus induced acceleration of autoimmune diabetes in bb rats
url http://dx.doi.org/10.1080/10446670310001626517
work_keys_str_mv AT janluukhillebrands roleofperitonealmacrophagesincytomegalovirusinducedaccelerationofautoimmunediabetesinbbrats
AT nienkevanderwerf roleofperitonealmacrophagesincytomegalovirusinducedaccelerationofautoimmunediabetesinbbrats
AT flipaklatter roleofperitonealmacrophagesincytomegalovirusinducedaccelerationofautoimmunediabetesinbbrats
AT cathrienabruggeman roleofperitonealmacrophagesincytomegalovirusinducedaccelerationofautoimmunediabetesinbbrats
AT janrozing roleofperitonealmacrophagesincytomegalovirusinducedaccelerationofautoimmunediabetesinbbrats