L-arginine mitigates cardiac lipid and glucose accumulation through leptin modulation and enhancement of PIK3 activities in high fat-fed male Wistar rats

L-arginine mitigates cardiac lipid and glucose accumulation through leptin modulation and enhancement of PIK3 activities in high fat-fed male Wistar rats

Abstract Background and aim Insulin resistance and other metabolic risk factors are associated with increased cardiovascular diseases in animals fed with high fat diets (HFD). L-arginine is a semi-essential amino acid produced both endogenously and taken in the diet as supplements. It has been docum...

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Bibliographic Details
Main Authors: Adewumi Oluwafemi Oyabambi, Olubayode Bamidele, Blessing Boluwatife Aindero, Adeoba Mobolaji Awolola
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Nutrition & Metabolism
Subjects:
Atherogenic markers
Insulin resistance
L-Arginine
Leptin
Phosphoinositide 3-kinase
Online Access:https://doi.org/10.1186/s12986-024-00852-6
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