Unlocking efficiency in real-world collaborative studies: a multi-site international study with one-shot lossless GLMM algorithm

Unlocking efficiency in real-world collaborative studies: a multi-site international study with one-shot lossless GLMM algorithm

Abstract The widespread adoption of real-world data has given rise to numerous healthcare-distributed research networks, but multi-site analyses still face administrative burdens and data privacy challenges. In response, we developed a Collaborative One-shot Lossless Algorithm for Generalized Linear...

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Main Authors: Jiayi Tong, Jenna M. Reps, Chongliang Luo, Yiwen Lu, Lu Li, Juan Manuel Ramirez-Anguita, Milou T. Brand, Scott L. DuVall, Thomas Falconer, Alex Mayer Fuentes, Xing He, Michael E. Matheny, Miguel A. Mayer, Bhavnisha K. Patel, Katherine R. Simon, Marc A. Suchard, Guojun Tang, Benjamin Viernes, Ross D. Williams, Mui van Zandt, Fei Wang, Jiang Bian, Jiayu Zhou, David A. Asch, Yong Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01846-1
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