Supplementation with Potato Protein Concentrate and <i>Saccharomyces boulardii</i> to an Antibiotic-Free Diet Improves Intestinal Health in Weaned Piglets
Many countries have banned the use of antibiotics in livestock feed due to the development of antibiotic-resistant bacteria. Therefore, it is necessary to identify suitable alternatives to antibiotics in order to maintain intestinal health and improve piglet performance after weaning. The objective...
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2025-03-01
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| author | Tércia Cesária Reis de Souza Gerardo Mariscal Landín Ulisses Moreno Celis Teresita Hijuitl Valeriano José Guadalupe Gómez-Soto Christian Narváez Briones |
| author_facet | Tércia Cesária Reis de Souza Gerardo Mariscal Landín Ulisses Moreno Celis Teresita Hijuitl Valeriano José Guadalupe Gómez-Soto Christian Narváez Briones |
| author_sort | Tércia Cesária Reis de Souza |
| collection | DOAJ |
| description | Many countries have banned the use of antibiotics in livestock feed due to the development of antibiotic-resistant bacteria. Therefore, it is necessary to identify suitable alternatives to antibiotics in order to maintain intestinal health and improve piglet performance after weaning. The objective of this study was to evaluate how the intake of two functional foods—potato protein concentrate (PP) and <i>Saccharomyces boulardii</i> (Sb), either isolated or combined—would affect productive performance and some digestive morphophysiological responses after two weeks post-weaning. We evaluated five diets: SB, with Sb; PPC, with PP; PPC-SB, with a combination of PP and Sb; C−, without antibiotics, Sb, or PP; and C+, with antibiotics. Neither the absence of antibiotics in the diet nor the inclusion of PP and Sb affected performance or digestive organ development during the post-weaning phase. Piglets fed the C+ diet and the PP-Sb combination had higher concentrations of occludin proteins and longer villi in the jejunum compared to those fed C−, PPC, and SB. The use of Sb alone or in combination with PP increased fecal Lactobacillus, while antibiotics reduced coliform bacteria. The PP-Sb combination prevented the atrophy of the jejunal villi and promoted adhesion between enterocytes in the jejunum. Including these functional foods in piglet diets contributed to maintaining intestinal health during the critical post-weaning phase. However, further research is needed to validate and enhance the conclusions of this study. |
| format | Article |
| id | doaj-art-11bdfd9146ff495da93df263db8dec6a |
| institution | DOAJ |
| issn | 2076-2615 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj-art-11bdfd9146ff495da93df263db8dec6a2025-08-20T03:08:43ZengMDPI AGAnimals2076-26152025-03-0115798510.3390/ani15070985Supplementation with Potato Protein Concentrate and <i>Saccharomyces boulardii</i> to an Antibiotic-Free Diet Improves Intestinal Health in Weaned PigletsTércia Cesária Reis de Souza0Gerardo Mariscal Landín1Ulisses Moreno Celis2Teresita Hijuitl Valeriano3José Guadalupe Gómez-Soto4Christian Narváez Briones5Faculty of Natural Sciences, Autonomous University of Querétaro, Querétaro 76230, MexicoNational Institute of Agricultural and Livestock Forestry Research, National Center of Research in Animal Physiology, Ajuchitlán Colón, Querétaro 76280, MexicoFaculty of Natural Sciences, Autonomous University of Querétaro, Querétaro 76230, MexicoFaculty of Natural Sciences, Autonomous University of Querétaro, Querétaro 76230, MexicoFaculty of Natural Sciences, Autonomous University of Querétaro, Querétaro 76230, MexicoFaculty of Natural Sciences, Autonomous University of Querétaro, Querétaro 76230, MexicoMany countries have banned the use of antibiotics in livestock feed due to the development of antibiotic-resistant bacteria. Therefore, it is necessary to identify suitable alternatives to antibiotics in order to maintain intestinal health and improve piglet performance after weaning. The objective of this study was to evaluate how the intake of two functional foods—potato protein concentrate (PP) and <i>Saccharomyces boulardii</i> (Sb), either isolated or combined—would affect productive performance and some digestive morphophysiological responses after two weeks post-weaning. We evaluated five diets: SB, with Sb; PPC, with PP; PPC-SB, with a combination of PP and Sb; C−, without antibiotics, Sb, or PP; and C+, with antibiotics. Neither the absence of antibiotics in the diet nor the inclusion of PP and Sb affected performance or digestive organ development during the post-weaning phase. Piglets fed the C+ diet and the PP-Sb combination had higher concentrations of occludin proteins and longer villi in the jejunum compared to those fed C−, PPC, and SB. The use of Sb alone or in combination with PP increased fecal Lactobacillus, while antibiotics reduced coliform bacteria. The PP-Sb combination prevented the atrophy of the jejunal villi and promoted adhesion between enterocytes in the jejunum. Including these functional foods in piglet diets contributed to maintaining intestinal health during the critical post-weaning phase. However, further research is needed to validate and enhance the conclusions of this study.https://www.mdpi.com/2076-2615/15/7/985pigletsoccludinsintestinal permeabilityfunctional foodsprobiotics |
| spellingShingle | Tércia Cesária Reis de Souza Gerardo Mariscal Landín Ulisses Moreno Celis Teresita Hijuitl Valeriano José Guadalupe Gómez-Soto Christian Narváez Briones Supplementation with Potato Protein Concentrate and <i>Saccharomyces boulardii</i> to an Antibiotic-Free Diet Improves Intestinal Health in Weaned Piglets Animals piglets occludins intestinal permeability functional foods probiotics |
| title | Supplementation with Potato Protein Concentrate and <i>Saccharomyces boulardii</i> to an Antibiotic-Free Diet Improves Intestinal Health in Weaned Piglets |
| title_full | Supplementation with Potato Protein Concentrate and <i>Saccharomyces boulardii</i> to an Antibiotic-Free Diet Improves Intestinal Health in Weaned Piglets |
| title_fullStr | Supplementation with Potato Protein Concentrate and <i>Saccharomyces boulardii</i> to an Antibiotic-Free Diet Improves Intestinal Health in Weaned Piglets |
| title_full_unstemmed | Supplementation with Potato Protein Concentrate and <i>Saccharomyces boulardii</i> to an Antibiotic-Free Diet Improves Intestinal Health in Weaned Piglets |
| title_short | Supplementation with Potato Protein Concentrate and <i>Saccharomyces boulardii</i> to an Antibiotic-Free Diet Improves Intestinal Health in Weaned Piglets |
| title_sort | supplementation with potato protein concentrate and i saccharomyces boulardii i to an antibiotic free diet improves intestinal health in weaned piglets |
| topic | piglets occludins intestinal permeability functional foods probiotics |
| url | https://www.mdpi.com/2076-2615/15/7/985 |
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