Interaction of RECQL4 with poly(ADP‐ribose) is critical for the DNA double‐strand break response in human cells

Interaction of RECQL4 with poly(ADP‐ribose) is critical for the DNA double‐strand break response in human cells

To overcome genotoxicity, cells have evolved powerful and effective mechanisms to detect and respond to DNA lesions. RecQ Like Helicase‐4 (RECQL4) plays a vital role in DNA damage responses. RECQL4 is recruited to DNA double‐strand break (DSB) sites in a poly(ADP‐ribosyl)ation (PARylation)‐dependent...

Full description

Saved in:
Bibliographic Details
Main Authors: Sunyoung Shin, Dongmin Kim, Hyemi Kim, Won‐Ho Cho, Gyungmin Kim, Joon‐Kyu Lee
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:FEBS Open Bio
Subjects:
DNA double‐strand breaks
DNA repair
poly(ADP‐ribose) binding motif
poly(ADP‐ribosyl)ation
RECQL4
Online Access:https://doi.org/10.1002/2211-5463.13917
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items