The Influence of Obesity on Different Genders in Patients with Obstructive Sleep Apnea

Obesity is considered to be a major contributing factor to obstructive sleep apnea (OSA); however, there is limited evidence with regard to gender predominance. We analyzed 2345 patients (339 females) in correlation with body mass index (BMI) and OSA severity. Male AHIs were significantly higher tha...

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Main Authors: Kuo-Tung Huang, Chien-Hung Chin, Chia-Cheng Tseng, Huang-Chih Chang, Yung-Che Chen, Chin-Chou Wang, Meng-Chih Lin, Hsin-Ching Lin, Mao-Chang Su
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/487215
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author Kuo-Tung Huang
Chien-Hung Chin
Chia-Cheng Tseng
Huang-Chih Chang
Yung-Che Chen
Chin-Chou Wang
Meng-Chih Lin
Hsin-Ching Lin
Mao-Chang Su
author_facet Kuo-Tung Huang
Chien-Hung Chin
Chia-Cheng Tseng
Huang-Chih Chang
Yung-Che Chen
Chin-Chou Wang
Meng-Chih Lin
Hsin-Ching Lin
Mao-Chang Su
author_sort Kuo-Tung Huang
collection DOAJ
description Obesity is considered to be a major contributing factor to obstructive sleep apnea (OSA); however, there is limited evidence with regard to gender predominance. We analyzed 2345 patients (339 females) in correlation with body mass index (BMI) and OSA severity. Male AHIs were significantly higher than female AHIs in each BMI group. As the BMI increased, the AHI increased in both males and females, and this trend was more obvious in males. For BMI-matched male and female patients with OSA, the severity of OSA was higher in males. As BMI increased, the severity of OSA increased more obviously in males. Our findings suggest that increased body fat contributes to the pathogenesis of OSA more in males than in females and that obesity plays a more significant role in contributing to OSA in male patients.
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publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-11abd7c9bc06421f841688aea3aefc7a2025-08-20T03:54:11ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/487215487215The Influence of Obesity on Different Genders in Patients with Obstructive Sleep ApneaKuo-Tung Huang0Chien-Hung Chin1Chia-Cheng Tseng2Huang-Chih Chang3Yung-Che Chen4Chin-Chou Wang5Meng-Chih Lin6Hsin-Ching Lin7Mao-Chang Su8Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanSleep Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanObesity is considered to be a major contributing factor to obstructive sleep apnea (OSA); however, there is limited evidence with regard to gender predominance. We analyzed 2345 patients (339 females) in correlation with body mass index (BMI) and OSA severity. Male AHIs were significantly higher than female AHIs in each BMI group. As the BMI increased, the AHI increased in both males and females, and this trend was more obvious in males. For BMI-matched male and female patients with OSA, the severity of OSA was higher in males. As BMI increased, the severity of OSA increased more obviously in males. Our findings suggest that increased body fat contributes to the pathogenesis of OSA more in males than in females and that obesity plays a more significant role in contributing to OSA in male patients.http://dx.doi.org/10.1155/2014/487215
spellingShingle Kuo-Tung Huang
Chien-Hung Chin
Chia-Cheng Tseng
Huang-Chih Chang
Yung-Che Chen
Chin-Chou Wang
Meng-Chih Lin
Hsin-Ching Lin
Mao-Chang Su
The Influence of Obesity on Different Genders in Patients with Obstructive Sleep Apnea
The Scientific World Journal
title The Influence of Obesity on Different Genders in Patients with Obstructive Sleep Apnea
title_full The Influence of Obesity on Different Genders in Patients with Obstructive Sleep Apnea
title_fullStr The Influence of Obesity on Different Genders in Patients with Obstructive Sleep Apnea
title_full_unstemmed The Influence of Obesity on Different Genders in Patients with Obstructive Sleep Apnea
title_short The Influence of Obesity on Different Genders in Patients with Obstructive Sleep Apnea
title_sort influence of obesity on different genders in patients with obstructive sleep apnea
url http://dx.doi.org/10.1155/2014/487215
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