Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study

To compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine. Method Sixty patients, both genders, aged between 18 and 50 years, with a diagnosis of chronic migraine, were randomized in groups called amitriptyline and ae...

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Main Authors: Michelle Dias Santos Santiago, Deusvenir de Souza Carvalho, Alberto Alain Gabbai, Mariana Machado Pereira Pinto, Andrea Regina Correa Moutran, Thais Rodrigues Villa
Format: Article
Language:English
Published: Thieme Revinter Publicações 2014-11-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014001100851&lng=en&tlng=en
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author Michelle Dias Santos Santiago
Deusvenir de Souza Carvalho
Alberto Alain Gabbai
Mariana Machado Pereira Pinto
Andrea Regina Correa Moutran
Thais Rodrigues Villa
author_facet Michelle Dias Santos Santiago
Deusvenir de Souza Carvalho
Alberto Alain Gabbai
Mariana Machado Pereira Pinto
Andrea Regina Correa Moutran
Thais Rodrigues Villa
author_sort Michelle Dias Santos Santiago
collection DOAJ
description To compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine. Method Sixty patients, both genders, aged between 18 and 50 years, with a diagnosis of chronic migraine, were randomized in groups called amitriptyline and aerobic exercise or amitriptyline alone. The following parameters were evaluated: headache frequency, intensity and duration of headache, days of the analgesic medication use, body mass index (BMI), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) scores. Results In the evaluated parameters, was observed decrease in headache frequency (p=0.001), moderate intensity (p=0.048), in headache duration (p=0.001), the body mass index (p=0.001), Beck Depression Inventory (p=0.001) and Beck Anxiety Inventory scores (p=0.001), when groups were compared in the end of third month. Conclusion In this study, the amitriptyline was an effective treatment for chronic migraine, but its efficacy was increased when combined with aerobic exercise.
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series Arquivos de Neuro-Psiquiatria
spelling doaj-art-119da054186a48a3a9e3abb0530fc4df2025-08-20T03:54:12ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272014-11-01721185185510.1590/0004-282X20140148S0004-282X2014001100851Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative studyMichelle Dias Santos SantiagoDeusvenir de Souza CarvalhoAlberto Alain GabbaiMariana Machado Pereira PintoAndrea Regina Correa MoutranThais Rodrigues VillaTo compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine. Method Sixty patients, both genders, aged between 18 and 50 years, with a diagnosis of chronic migraine, were randomized in groups called amitriptyline and aerobic exercise or amitriptyline alone. The following parameters were evaluated: headache frequency, intensity and duration of headache, days of the analgesic medication use, body mass index (BMI), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) scores. Results In the evaluated parameters, was observed decrease in headache frequency (p=0.001), moderate intensity (p=0.048), in headache duration (p=0.001), the body mass index (p=0.001), Beck Depression Inventory (p=0.001) and Beck Anxiety Inventory scores (p=0.001), when groups were compared in the end of third month. Conclusion In this study, the amitriptyline was an effective treatment for chronic migraine, but its efficacy was increased when combined with aerobic exercise.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014001100851&lng=en&tlng=enmigrânea crônicaadultosprofilaxiaamitriptilinaexercício aeróbio
spellingShingle Michelle Dias Santos Santiago
Deusvenir de Souza Carvalho
Alberto Alain Gabbai
Mariana Machado Pereira Pinto
Andrea Regina Correa Moutran
Thais Rodrigues Villa
Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study
Arquivos de Neuro-Psiquiatria
migrânea crônica
adultos
profilaxia
amitriptilina
exercício aeróbio
title Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study
title_full Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study
title_fullStr Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study
title_full_unstemmed Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study
title_short Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study
title_sort amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine a randomized comparative study
topic migrânea crônica
adultos
profilaxia
amitriptilina
exercício aeróbio
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014001100851&lng=en&tlng=en
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