A novel Fc-enhanced humanized monoclonal antibody targeting B7-H3 suppresses the growth of ESCC

A novel Fc-enhanced humanized monoclonal antibody targeting B7-H3 suppresses the growth of ESCC

Esophageal squamous cell carcinoma (ESCC) is a prevalent malignant tumor of the digestive tract with a low 5-year survival rate due to the lack of effective treatment methods. Although therapeutic monoclonal antibodies (mAbs) now play an important role in cancer therapy, effective targeted mAbs are...

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Bibliographic Details
Main Authors: Huiting Wu, Chang Liu, Qiang Yuan, Yan Qiao, Yongwei Ding, Lina Duan, Wenjing Li, Mengjia Zhang, Xuhua Zhang, Yanan Jiang, Jing Lu, Ziming Dong, Tao Wang, Kangdong Liu, Jimin Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
ADCC
B7-H3
Esophageal squamous cell carcinoma
Fc engineering
monoclonal antibody
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2282250
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