Triglyceride-glucose index predicts cognitive decline and striatal dopamine deficiency in Parkinson disease in two cohorts

Abstract Heterogeneity is an important feature of cognitive impairment in patients with Parkinson’s disease (PD), with emerging evidence linking insulin resistance to accelerated cognitive decline. Our investigation examined the relationship between the triglyceride-glucose (TyG) index-a marker of i...

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Bibliographic Details
Main Authors: Huimin Cao, Yuying Zhao, Ziyi Chen, Xiaoya Zou, Xinyi Du, Li Yi, Yu Ai, Hongzhou Zuo, Oumei Cheng, Parkinson’s Progression Markers Initiative
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01100-1
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