Relationship between intolerance of uncertainty and obsessive-compulsive disorder pathology and neurobiological mechanisms

Obsessive-compulsive disorder (OCD) is a highly disabling mental disorder that impairs patients' social function and quality of life, and impose a substantial economic burden. Intolerance of uncertainty (IU) refers to a cognitive bias in perceiving, interpreting and responding to uncertain situ...

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Bibliographic Details
Main Authors: Li Bin, Jiang Jiaxin, Li Hailong, Zheng Zhong, Huang Xiaoqi
Format: Article
Language:zho
Published: Editorial Office of Sichuan Mental Health 2025-06-01
Series:Sichuan jingshen weisheng
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Online Access:http://www.psychjm.net.cn/scjswszz/ch/reader/view_abstract.aspx?file_no=202503001&flag=1
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Summary:Obsessive-compulsive disorder (OCD) is a highly disabling mental disorder that impairs patients' social function and quality of life, and impose a substantial economic burden. Intolerance of uncertainty (IU) refers to a cognitive bias in perceiving, interpreting and responding to uncertain situations or events. IU is closely associated with the cognitive patterns of OCD patients. Based on magnetic resonance imaging (MRI), this paper discusses the research progress of the relationship between IU and psychopathological characteristics of OCD, and put forward the research direction, aims to provide evidence-based references for the development of optimized therapeutic interventions for OCD.
ISSN:1007-3256