ANALYSIS OF THE HISTOLOGICAL STUDY OF THE INFLUENCE OF THE BREAST IMPLANT SHELL ON THE SURROUNDING TISSUES IN THE EXPERIMENT

Introduction. Breast implants are widely used for cosmetic augmentation and reconstruction of the breast after mastectomy. Today, many types of breast implants are available, which differ in different physical characteristics, such as shape, size, gel material and surface texture, and also differ in...

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Main Authors: Iryna M. Shmyhina, Yurii D. Pidchenko, Oleksandr V. Khrapach, Vasyl V. Khrapach
Format: Article
Language:English
Published: State Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative Department 2025-01-01
Series:Клінічна та профілактична медицина
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Online Access:https://cp-medical.com/index.php/journal/article/view/517
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author Iryna M. Shmyhina
Yurii D. Pidchenko
Oleksandr V. Khrapach
Vasyl V. Khrapach
author_facet Iryna M. Shmyhina
Yurii D. Pidchenko
Oleksandr V. Khrapach
Vasyl V. Khrapach
author_sort Iryna M. Shmyhina
collection DOAJ
description Introduction. Breast implants are widely used for cosmetic augmentation and reconstruction of the breast after mastectomy. Today, many types of breast implants are available, which differ in different physical characteristics, such as shape, size, gel material and surface texture, and also differ in the chemical composition of the implant components, such as the elastomeric shell. Aim. To study in the experiment the process of formation of the peri-implant capsule around the latest generation prostheses, which are currently widely used in clinical practice. Materials and methods. The study was carried out in two stages: the first – experimental (modeling for the purpose of morphohistological assessment of changes in the influence of the structure of the breast endoprosthesis on paraimplant tissues) the second – histological. Results and discussion. Histological observations help to provide a biological context for quantitative measurements and a basis for better understanding the role of implant surface texture features in clinical settings. The relevance of such research is demonstrated by a number of similar studies in other countries, which included imaging analysis and in vitro assessment of adhesion of fibroblasts, macrophages or bacteria to the shell surface, but did not link these factors to in vivo data [8]. Characterization of the physical properties of implant surfaces is key to understanding how surface texture can influence tissue response to breast implants. Conclusions. Analyzing the data of the histological study of the influence of the breast implant shell on the surrounding tissues in the experiment, it can be concluded that when using modern implants of the latest generation, a thinner periprosthetic capsule is formed, especially in the part not covered by muscle; that when using the main types of modern breast implants, an insufficiently dense periprosthetic capsule is formed, which leads to distal and lateral ptosis of the implant and the breast in the late postoperative period.
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spelling doaj-art-11805a57cae44de4bdad09ca5531fb0a2025-08-20T02:34:31ZengState Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative DepartmentКлінічна та профілактична медицина2616-48682025-01-011788510.31612/2616-4868.1.2025.10517ANALYSIS OF THE HISTOLOGICAL STUDY OF THE INFLUENCE OF THE BREAST IMPLANT SHELL ON THE SURROUNDING TISSUES IN THE EXPERIMENTIryna M. Shmyhina0Yurii D. Pidchenko1Oleksandr V. Khrapach2Vasyl V. Khrapach3Department of plastic and reconstructive surgery of the Institute of Postgraduate Education, O.O. Bogomolets National Medical University, Kyiv, UkraineDepartment of plastic and reconstructive surgery of the Institute of Postgraduate Education, O.O. Bogomolets National Medical University, Kyiv, UkraineDepartment of plastic and reconstructive surgery of the Institute of Postgraduate Education, O.O. Bogomolets National Medical University, Kyiv, UkraineDepartment of plastic and reconstructive surgery of the Institute of Postgraduate Education, O.O. Bogomolets National Medical University, Kyiv, UkraineIntroduction. Breast implants are widely used for cosmetic augmentation and reconstruction of the breast after mastectomy. Today, many types of breast implants are available, which differ in different physical characteristics, such as shape, size, gel material and surface texture, and also differ in the chemical composition of the implant components, such as the elastomeric shell. Aim. To study in the experiment the process of formation of the peri-implant capsule around the latest generation prostheses, which are currently widely used in clinical practice. Materials and methods. The study was carried out in two stages: the first – experimental (modeling for the purpose of morphohistological assessment of changes in the influence of the structure of the breast endoprosthesis on paraimplant tissues) the second – histological. Results and discussion. Histological observations help to provide a biological context for quantitative measurements and a basis for better understanding the role of implant surface texture features in clinical settings. The relevance of such research is demonstrated by a number of similar studies in other countries, which included imaging analysis and in vitro assessment of adhesion of fibroblasts, macrophages or bacteria to the shell surface, but did not link these factors to in vivo data [8]. Characterization of the physical properties of implant surfaces is key to understanding how surface texture can influence tissue response to breast implants. Conclusions. Analyzing the data of the histological study of the influence of the breast implant shell on the surrounding tissues in the experiment, it can be concluded that when using modern implants of the latest generation, a thinner periprosthetic capsule is formed, especially in the part not covered by muscle; that when using the main types of modern breast implants, an insufficiently dense periprosthetic capsule is formed, which leads to distal and lateral ptosis of the implant and the breast in the late postoperative period.https://cp-medical.com/index.php/journal/article/view/517shelltissue reactionbreast implantexperimental studyperi-implant tissues
spellingShingle Iryna M. Shmyhina
Yurii D. Pidchenko
Oleksandr V. Khrapach
Vasyl V. Khrapach
ANALYSIS OF THE HISTOLOGICAL STUDY OF THE INFLUENCE OF THE BREAST IMPLANT SHELL ON THE SURROUNDING TISSUES IN THE EXPERIMENT
Клінічна та профілактична медицина
shell
tissue reaction
breast implant
experimental study
peri-implant tissues
title ANALYSIS OF THE HISTOLOGICAL STUDY OF THE INFLUENCE OF THE BREAST IMPLANT SHELL ON THE SURROUNDING TISSUES IN THE EXPERIMENT
title_full ANALYSIS OF THE HISTOLOGICAL STUDY OF THE INFLUENCE OF THE BREAST IMPLANT SHELL ON THE SURROUNDING TISSUES IN THE EXPERIMENT
title_fullStr ANALYSIS OF THE HISTOLOGICAL STUDY OF THE INFLUENCE OF THE BREAST IMPLANT SHELL ON THE SURROUNDING TISSUES IN THE EXPERIMENT
title_full_unstemmed ANALYSIS OF THE HISTOLOGICAL STUDY OF THE INFLUENCE OF THE BREAST IMPLANT SHELL ON THE SURROUNDING TISSUES IN THE EXPERIMENT
title_short ANALYSIS OF THE HISTOLOGICAL STUDY OF THE INFLUENCE OF THE BREAST IMPLANT SHELL ON THE SURROUNDING TISSUES IN THE EXPERIMENT
title_sort analysis of the histological study of the influence of the breast implant shell on the surrounding tissues in the experiment
topic shell
tissue reaction
breast implant
experimental study
peri-implant tissues
url https://cp-medical.com/index.php/journal/article/view/517
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AT oleksandrvkhrapach analysisofthehistologicalstudyoftheinfluenceofthebreastimplantshellonthesurroundingtissuesintheexperiment
AT vasylvkhrapach analysisofthehistologicalstudyoftheinfluenceofthebreastimplantshellonthesurroundingtissuesintheexperiment