Managing Sleep Disturbances in Cirrhosis
Sleep disturbances, particularly daytime sleepiness and insomnia, are common problems reported by patients suffering from liver cirrhosis. Poor sleep negatively impacts patients’ quality of life and cognitive functions and increases mortality. Although sleep disturbances can be an early sign of hepa...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Scientifica |
| Online Access: | http://dx.doi.org/10.1155/2016/6576812 |
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| _version_ | 1850236741034704896 |
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| author | Xun Zhao Philip Wong |
| author_facet | Xun Zhao Philip Wong |
| author_sort | Xun Zhao |
| collection | DOAJ |
| description | Sleep disturbances, particularly daytime sleepiness and insomnia, are common problems reported by patients suffering from liver cirrhosis. Poor sleep negatively impacts patients’ quality of life and cognitive functions and increases mortality. Although sleep disturbances can be an early sign of hepatic encephalopathy (HE), many patients without HE still complain of poor quality sleep. The pathophysiology of these disturbances is not fully understood but is believed to be linked to impaired hepatic melatonin metabolism. This paper provides an overview for the clinician of common comorbidities contributing to poor sleep in patients with liver disease, mainly restless leg syndrome and obstructive sleep apnea. It discusses nondrug and pharmacologic treatment options in these patients, such as the use of light therapy and histamine (H1) blockers. |
| format | Article |
| id | doaj-art-117dbad2a7f94e0fa28acc7a2b4a5cd3 |
| institution | OA Journals |
| issn | 2090-908X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Scientifica |
| spelling | doaj-art-117dbad2a7f94e0fa28acc7a2b4a5cd32025-08-20T02:01:54ZengWileyScientifica2090-908X2016-01-01201610.1155/2016/65768126576812Managing Sleep Disturbances in CirrhosisXun Zhao0Philip Wong1Department of Gastroenterology and Hepatology, Royal Victoria Hospital, McGill University, 1001 Boulevard Decarie, Montreal, QC, H4A 3J1, CanadaDepartment of Gastroenterology and Hepatology, Royal Victoria Hospital, McGill University, 1001 Boulevard Decarie, Montreal, QC, H4A 3J1, CanadaSleep disturbances, particularly daytime sleepiness and insomnia, are common problems reported by patients suffering from liver cirrhosis. Poor sleep negatively impacts patients’ quality of life and cognitive functions and increases mortality. Although sleep disturbances can be an early sign of hepatic encephalopathy (HE), many patients without HE still complain of poor quality sleep. The pathophysiology of these disturbances is not fully understood but is believed to be linked to impaired hepatic melatonin metabolism. This paper provides an overview for the clinician of common comorbidities contributing to poor sleep in patients with liver disease, mainly restless leg syndrome and obstructive sleep apnea. It discusses nondrug and pharmacologic treatment options in these patients, such as the use of light therapy and histamine (H1) blockers.http://dx.doi.org/10.1155/2016/6576812 |
| spellingShingle | Xun Zhao Philip Wong Managing Sleep Disturbances in Cirrhosis Scientifica |
| title | Managing Sleep Disturbances in Cirrhosis |
| title_full | Managing Sleep Disturbances in Cirrhosis |
| title_fullStr | Managing Sleep Disturbances in Cirrhosis |
| title_full_unstemmed | Managing Sleep Disturbances in Cirrhosis |
| title_short | Managing Sleep Disturbances in Cirrhosis |
| title_sort | managing sleep disturbances in cirrhosis |
| url | http://dx.doi.org/10.1155/2016/6576812 |
| work_keys_str_mv | AT xunzhao managingsleepdisturbancesincirrhosis AT philipwong managingsleepdisturbancesincirrhosis |