Cannabinoids and Their Role in Chronic Pain Treatment: Current Concepts and a Comprehensive Review

For decades, chronic pain was managed with an almost conventional approach of using a wide range of analgesic spectrum, surgical approaches and complex interventional pain techniques to modulate or even interrupt pain pathways. These different approaches carry many pharmacological hazards together...

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Main Authors: Islam Shehata, Ahmed Hashim, Ahmed Saad Elsaeidy, Anagha Nair, Ivan Urits, Omar Viswanath, Alan D. Kaye, Marian Habib
Format: Article
Language:English
Published: Open Medical Publishing 2022-10-01
Series:Health Psychology Research
Online Access:https://doi.org/10.52965/001c.35848
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author Islam Shehata
Ahmed Hashim
Ahmed Saad Elsaeidy
Anagha Nair
Ivan Urits
Omar Viswanath
Alan D. Kaye
Marian Habib
author_facet Islam Shehata
Ahmed Hashim
Ahmed Saad Elsaeidy
Anagha Nair
Ivan Urits
Omar Viswanath
Alan D. Kaye
Marian Habib
author_sort Islam Shehata
collection DOAJ
description For decades, chronic pain was managed with an almost conventional approach of using a wide range of analgesic spectrum, surgical approaches and complex interventional pain techniques to modulate or even interrupt pain pathways. These different approaches carry many pharmacological hazards together with the lack of efficacy and safety of many interventional and surgical management techniques for chronic pain have mandated searching for other effective therapies including alternative treatments. Cannabinoids are naturally occurring substances that are derived from Cannabis sativa L. The usage of cannabinoids and their related synthetic chemical compounds has emerged as a choice in the management of different chronic pain conditions is being evaluated, however, the efficacy is still not consistently established. In the present investigation, therefore, we discuss the different aspects related to cannabinoids and their implications in the management of chronic pain conditions. This review will also discuss the safety profile of the cannabinoids together with the legal considerations that hinder their use in different countries.
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institution Kabale University
issn 2420-8124
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publishDate 2022-10-01
publisher Open Medical Publishing
record_format Article
series Health Psychology Research
spelling doaj-art-116841aae62246acbf09b685ef6e48602025-02-11T20:30:37ZengOpen Medical PublishingHealth Psychology Research2420-81242022-10-01104Cannabinoids and Their Role in Chronic Pain Treatment: Current Concepts and a Comprehensive ReviewIslam ShehataAhmed HashimAhmed Saad ElsaeidyAnagha NairIvan UritsOmar ViswanathAlan D. KayeMarian HabibFor decades, chronic pain was managed with an almost conventional approach of using a wide range of analgesic spectrum, surgical approaches and complex interventional pain techniques to modulate or even interrupt pain pathways. These different approaches carry many pharmacological hazards together with the lack of efficacy and safety of many interventional and surgical management techniques for chronic pain have mandated searching for other effective therapies including alternative treatments. Cannabinoids are naturally occurring substances that are derived from Cannabis sativa L. The usage of cannabinoids and their related synthetic chemical compounds has emerged as a choice in the management of different chronic pain conditions is being evaluated, however, the efficacy is still not consistently established. In the present investigation, therefore, we discuss the different aspects related to cannabinoids and their implications in the management of chronic pain conditions. This review will also discuss the safety profile of the cannabinoids together with the legal considerations that hinder their use in different countries.https://doi.org/10.52965/001c.35848
spellingShingle Islam Shehata
Ahmed Hashim
Ahmed Saad Elsaeidy
Anagha Nair
Ivan Urits
Omar Viswanath
Alan D. Kaye
Marian Habib
Cannabinoids and Their Role in Chronic Pain Treatment: Current Concepts and a Comprehensive Review
Health Psychology Research
title Cannabinoids and Their Role in Chronic Pain Treatment: Current Concepts and a Comprehensive Review
title_full Cannabinoids and Their Role in Chronic Pain Treatment: Current Concepts and a Comprehensive Review
title_fullStr Cannabinoids and Their Role in Chronic Pain Treatment: Current Concepts and a Comprehensive Review
title_full_unstemmed Cannabinoids and Their Role in Chronic Pain Treatment: Current Concepts and a Comprehensive Review
title_short Cannabinoids and Their Role in Chronic Pain Treatment: Current Concepts and a Comprehensive Review
title_sort cannabinoids and their role in chronic pain treatment current concepts and a comprehensive review
url https://doi.org/10.52965/001c.35848
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