Infectious encephalitis diagnosis and treatment in immunosupressed patients: a case report and review of literature
Infectious encephalitis in immunosuppressed patients is a common and urgent condition that requires rapid diagnosis and early treatment. The disease can lead to severe neurological deficit and eventually result in the death of the patient. Usually infectious encephalitis presents with fever, headac...
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| Format: | Article |
| Language: | English |
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Vilnius University Press
2019-06-01
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| Series: | Neurologijos seminarai |
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| Online Access: | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27794 |
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| author | M. Jokubaitis J. Valaikienė |
| author_facet | M. Jokubaitis J. Valaikienė |
| author_sort | M. Jokubaitis |
| collection | DOAJ |
| description |
Infectious encephalitis in immunosuppressed patients is a common and urgent condition that requires rapid diagnosis and early treatment. The disease can lead to severe neurological deficit and eventually result in the death of the patient. Usually infectious encephalitis presents with fever, headache, focal neurological deficits, and altered state of consciousness. Immunosuppressed patients pose a great differential diagnostic challenge since clinical symptoms, laboratory findings, and imaging tests are often attenuated and may imitate stroke or other non-infectious diseases. Therefore, infectious meningoencephalitis should be suspected in all immunosuppressed patients with acute focal neurological symptoms, even in the absence of fever and meningeal signs. Accordingly, physician should thoroughly evaluate patient’s history, perform detailed physical examination, and carefully interpret test results. Early diagnosis and initiation of appropriate treatment of bacterial meningoencephalitis correlates with better prognosis for the patient. This article describes an atypical clinical case of a bacterial meningoencephalitis with stroke-like symptoms in a patient with multiple myeloma. In addition, the article reviews clinical presentation, diagnostic and treatment recommendations of infectious encephalitis in immunosuppressed patients.
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| format | Article |
| id | doaj-art-11659214f5164f19a8db79e758fcae8f |
| institution | Kabale University |
| issn | 1392-3064 2424-5917 |
| language | English |
| publishDate | 2019-06-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Neurologijos seminarai |
| spelling | doaj-art-11659214f5164f19a8db79e758fcae8f2025-01-20T18:22:58ZengVilnius University PressNeurologijos seminarai1392-30642424-59172019-06-01232(80)10.29014/ns.2019.15Infectious encephalitis diagnosis and treatment in immunosupressed patients: a case report and review of literatureM. Jokubaitis 0J. Valaikienė 1Vilnius University, LithuaniaVilnius University, Lithuania Infectious encephalitis in immunosuppressed patients is a common and urgent condition that requires rapid diagnosis and early treatment. The disease can lead to severe neurological deficit and eventually result in the death of the patient. Usually infectious encephalitis presents with fever, headache, focal neurological deficits, and altered state of consciousness. Immunosuppressed patients pose a great differential diagnostic challenge since clinical symptoms, laboratory findings, and imaging tests are often attenuated and may imitate stroke or other non-infectious diseases. Therefore, infectious meningoencephalitis should be suspected in all immunosuppressed patients with acute focal neurological symptoms, even in the absence of fever and meningeal signs. Accordingly, physician should thoroughly evaluate patient’s history, perform detailed physical examination, and carefully interpret test results. Early diagnosis and initiation of appropriate treatment of bacterial meningoencephalitis correlates with better prognosis for the patient. This article describes an atypical clinical case of a bacterial meningoencephalitis with stroke-like symptoms in a patient with multiple myeloma. In addition, the article reviews clinical presentation, diagnostic and treatment recommendations of infectious encephalitis in immunosuppressed patients. https://www.journals.vu.lt/neurologijos_seminarai/article/view/27794neuroinfectionencephalitisimmunosuppressiondiagnosistreatment |
| spellingShingle | M. Jokubaitis J. Valaikienė Infectious encephalitis diagnosis and treatment in immunosupressed patients: a case report and review of literature Neurologijos seminarai neuroinfection encephalitis immunosuppression diagnosis treatment |
| title | Infectious encephalitis diagnosis and treatment in immunosupressed patients: a case report and review of literature |
| title_full | Infectious encephalitis diagnosis and treatment in immunosupressed patients: a case report and review of literature |
| title_fullStr | Infectious encephalitis diagnosis and treatment in immunosupressed patients: a case report and review of literature |
| title_full_unstemmed | Infectious encephalitis diagnosis and treatment in immunosupressed patients: a case report and review of literature |
| title_short | Infectious encephalitis diagnosis and treatment in immunosupressed patients: a case report and review of literature |
| title_sort | infectious encephalitis diagnosis and treatment in immunosupressed patients a case report and review of literature |
| topic | neuroinfection encephalitis immunosuppression diagnosis treatment |
| url | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27794 |
| work_keys_str_mv | AT mjokubaitis infectiousencephalitisdiagnosisandtreatmentinimmunosupressedpatientsacasereportandreviewofliterature AT jvalaikiene infectiousencephalitisdiagnosisandtreatmentinimmunosupressedpatientsacasereportandreviewofliterature |