Sonic Hedgehog potentiates BMP9-induced osteogenic differentiation of mesenchymal stem cells

Sonic Hedgehog potentiates BMP9-induced osteogenic differentiation of mesenchymal stem cells

Bone morphogenetic protein 9 (BMP9) has remarkable potential to induce the differentiation of mesenchymal stem cells (MSCs) towards the osteoblastic lineage. Additionally, research suggests that certain growth factors have the ability to potentiate BMP9-induced osteogenic differentiation of MSCs. So...

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Bibliographic Details
Main Authors: Lulu Zhang, Caixia Ji, Ziyun Li, Habu Jiwa, Zhou Xie, Xiaoji Luo, Jinyong Luo
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-05-01
Series:Genes and Diseases
Subjects:
BMP9
Bone defects
Bone morphogenetic proteins
Mesenchymal stem cells
Osteogenic differentiation
Sonic Hedgehog
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224001053
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