Immune checkpoint changes correlate with the progression and prognosis of amyotrophic lateral sclerosis

Immune checkpoint changes correlate with the progression and prognosis of amyotrophic lateral sclerosis

Background Amyotrophic lateral sclerosis (ALS) urgently requires robust biomarkers for early diagnosis and prognostic stratification. This study aims to investigate the diagnostic and prognostic potential of membrane-bound and soluble immune checkpoint molecules in ALS pathogenesis.Methods In the pr...

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Bibliographic Details
Main Authors: Sheng Chen, Chunzuan Xu, Changyun Liu, Jiaqi Li, Shupei Ke, Yingqian Lu, Yali Huang, Jialin Chen, Feifei Lin, Huapin Huang, Zhangyu Zou
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
Subjects:
Amyotrophic lateral sclerosis
immune checkpoints
PD-1
prognosis
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2025.2540023
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