Metabolic Activity in Human Intermuscular Adipose Tissue Directs the Response of Resident PPARγ<sup>+</sup> Macrophages to Fatty Acids

Metabolic Activity in Human Intermuscular Adipose Tissue Directs the Response of Resident PPARγ<sup>+</sup> Macrophages to Fatty Acids

<b>Background/Objectives</b>: Peroxisome proliferator-activated receptor gamma (PPARγ) is a fatty acid-binding transcription activator of the adipokine chemerin. The key role of PPARγ in adipogenesis was established by reports on adipose tissue-resident macrophages that express PPARγ. Th...

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Bibliographic Details
Main Authors: Xiaoying Chen, Sebastian Ludger Schubert, Aline Müller, Miguel Pishnamaz, Frank Hildebrand, Mahtab Nourbakhsh
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
PPARγ
macrophages
adipose tissue
fatty acids
mitochondria
VDAC1
Online Access:https://www.mdpi.com/2227-9059/13/1/10
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