Isolation, Structures, and Bioactivities of Polysaccharides from <i>Achyranthes bidentata</i>: A Review
<i>Achyranthes bidentata</i>, a traditional Chinese medicinal herb, has garnered significant attentions due to its diverse bioactivities and substantial market potential. Recent advancements in phytochemical and pharmacological research have identified polysaccharides as some of its prim...
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MDPI AG
2025-06-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/30/12/2523 |
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| author | Lin Li Zhihong Wang Wei Zhang Longxin Chen Yingying Yang Wan Yang Mengkun Li Chunhuan Yuan Limeng Zhang Linqing Wang |
| author_facet | Lin Li Zhihong Wang Wei Zhang Longxin Chen Yingying Yang Wan Yang Mengkun Li Chunhuan Yuan Limeng Zhang Linqing Wang |
| author_sort | Lin Li |
| collection | DOAJ |
| description | <i>Achyranthes bidentata</i>, a traditional Chinese medicinal herb, has garnered significant attentions due to its diverse bioactivities and substantial market potential. Recent advancements in phytochemical and pharmacological research have identified polysaccharides as some of its primary bioactive constituents. These polysaccharides demonstrate a wide range of biological effects both in vitro and in vivo, such as antioxidant, immunomodulatory, antitumor, anti-inflammatory, anti-osteoporotic, and gut microbiota-regulating properties. This review comprehensively examines the extraction and purification techniques, structural features, modifications, pharmacological effects, and structure–activity relationships of <i>A. bidentata</i> polysaccharides (ABPs) over the past three decades. By highlighting the multifaceted biological roles and structure–activity correlations of ABPs, this review aims to enhance the understanding of their potential applications and foster further innovation in bioactive research and development. |
| format | Article |
| id | doaj-art-11587f112b95444a9894de3ca8e3a78a |
| institution | Kabale University |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj-art-11587f112b95444a9894de3ca8e3a78a2025-08-20T03:27:40ZengMDPI AGMolecules1420-30492025-06-013012252310.3390/molecules30122523Isolation, Structures, and Bioactivities of Polysaccharides from <i>Achyranthes bidentata</i>: A ReviewLin Li0Zhihong Wang1Wei Zhang2Longxin Chen3Yingying Yang4Wan Yang5Mengkun Li6Chunhuan Yuan7Limeng Zhang8Linqing Wang9College of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, ChinaCollege of Special Education, Zhengzhou Normal University, Zhengzhou 450044, ChinaCollege of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, ChinaCollege of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, ChinaCollege of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, ChinaCollege of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, ChinaCollege of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, ChinaCollege of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, ChinaHenan Province Engineering Technology Research Center of Antibody Screening and Diagnostic, Zhengzhou 450044, ChinaCollege of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, China<i>Achyranthes bidentata</i>, a traditional Chinese medicinal herb, has garnered significant attentions due to its diverse bioactivities and substantial market potential. Recent advancements in phytochemical and pharmacological research have identified polysaccharides as some of its primary bioactive constituents. These polysaccharides demonstrate a wide range of biological effects both in vitro and in vivo, such as antioxidant, immunomodulatory, antitumor, anti-inflammatory, anti-osteoporotic, and gut microbiota-regulating properties. This review comprehensively examines the extraction and purification techniques, structural features, modifications, pharmacological effects, and structure–activity relationships of <i>A. bidentata</i> polysaccharides (ABPs) over the past three decades. By highlighting the multifaceted biological roles and structure–activity correlations of ABPs, this review aims to enhance the understanding of their potential applications and foster further innovation in bioactive research and development.https://www.mdpi.com/1420-3049/30/12/2523<i>Achyranthes bidentata</i>polysaccharidesstructural characterizationbioactivitystructure–activity relationships |
| spellingShingle | Lin Li Zhihong Wang Wei Zhang Longxin Chen Yingying Yang Wan Yang Mengkun Li Chunhuan Yuan Limeng Zhang Linqing Wang Isolation, Structures, and Bioactivities of Polysaccharides from <i>Achyranthes bidentata</i>: A Review Molecules <i>Achyranthes bidentata</i> polysaccharides structural characterization bioactivity structure–activity relationships |
| title | Isolation, Structures, and Bioactivities of Polysaccharides from <i>Achyranthes bidentata</i>: A Review |
| title_full | Isolation, Structures, and Bioactivities of Polysaccharides from <i>Achyranthes bidentata</i>: A Review |
| title_fullStr | Isolation, Structures, and Bioactivities of Polysaccharides from <i>Achyranthes bidentata</i>: A Review |
| title_full_unstemmed | Isolation, Structures, and Bioactivities of Polysaccharides from <i>Achyranthes bidentata</i>: A Review |
| title_short | Isolation, Structures, and Bioactivities of Polysaccharides from <i>Achyranthes bidentata</i>: A Review |
| title_sort | isolation structures and bioactivities of polysaccharides from i achyranthes bidentata i a review |
| topic | <i>Achyranthes bidentata</i> polysaccharides structural characterization bioactivity structure–activity relationships |
| url | https://www.mdpi.com/1420-3049/30/12/2523 |
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