Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History?
Pulsed field ablation (PFA) is a novel energy form for the catheter ablation of cardiac arrhythmias, which uses electrical fields to mediate myocardial death via irreversible electroporation and other modalities. It is believed to offer relative tissue specificity, lowering – or even eliminating – t...
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| Format: | Article |
| Language: | English |
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Radcliffe Medical Media
2024-03-01
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| Series: | Arrhythmia & Electrophysiology Review |
| Online Access: | https://www.aerjournal.com/articleindex/aer.2023.16 |
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| author | Moritz Nies Keita Watanabe Iwanari Kawamura Jacob S Koruth |
| author_facet | Moritz Nies Keita Watanabe Iwanari Kawamura Jacob S Koruth |
| author_sort | Moritz Nies |
| collection | DOAJ |
| description | Pulsed field ablation (PFA) is a novel energy form for the catheter ablation of cardiac arrhythmias, which uses electrical fields to mediate myocardial death via irreversible electroporation and other modalities. It is believed to offer relative tissue specificity, lowering – or even eliminating – the risk of complications associated with thermal energy, such as atrio-oesophageal fistulas. The proposed superior safety profile compared to thermal ablation has contributed to the enthusiastic implementation of PFA into clinical practice and is supported by early preclinical and clinical data. However, data about the effects of PFA on the oesophagus remain limited. This organ’s susceptibility to PFA has important clinical ramifications and there are two highly relevant questions. First, is the oesophagus absolutely spared by PFA or is there susceptibility to injury at higher field strengths? Second, if oesophageal injury can occur, can atrio-oesophageal fistulas ensue? The aim of this article is to provide a literature review on the effects of PFA on the oesophagus and to address these questions based on the data described. |
| format | Article |
| id | doaj-art-11497d71e88d42aeb9515696b8c4faaf |
| institution | OA Journals |
| issn | 2050-3369 2050-3377 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Arrhythmia & Electrophysiology Review |
| spelling | doaj-art-11497d71e88d42aeb9515696b8c4faaf2025-08-20T01:56:38ZengRadcliffe Medical MediaArrhythmia & Electrophysiology Review2050-33692050-33772024-03-011310.15420/aer.2023.16Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History?Moritz Nies0Keita Watanabe1Iwanari Kawamura2Jacob S Koruth3Helmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, NY, USHelmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, NY, USHelmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, NY, USHelmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, NY, USPulsed field ablation (PFA) is a novel energy form for the catheter ablation of cardiac arrhythmias, which uses electrical fields to mediate myocardial death via irreversible electroporation and other modalities. It is believed to offer relative tissue specificity, lowering – or even eliminating – the risk of complications associated with thermal energy, such as atrio-oesophageal fistulas. The proposed superior safety profile compared to thermal ablation has contributed to the enthusiastic implementation of PFA into clinical practice and is supported by early preclinical and clinical data. However, data about the effects of PFA on the oesophagus remain limited. This organ’s susceptibility to PFA has important clinical ramifications and there are two highly relevant questions. First, is the oesophagus absolutely spared by PFA or is there susceptibility to injury at higher field strengths? Second, if oesophageal injury can occur, can atrio-oesophageal fistulas ensue? The aim of this article is to provide a literature review on the effects of PFA on the oesophagus and to address these questions based on the data described.https://www.aerjournal.com/articleindex/aer.2023.16 |
| spellingShingle | Moritz Nies Keita Watanabe Iwanari Kawamura Jacob S Koruth Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History? Arrhythmia & Electrophysiology Review |
| title | Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History? |
| title_full | Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History? |
| title_fullStr | Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History? |
| title_full_unstemmed | Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History? |
| title_short | Endocardial Pulsed Field Ablation and the Oesophagus: Are Atrio-oesophageal Fistulas Now History? |
| title_sort | endocardial pulsed field ablation and the oesophagus are atrio oesophageal fistulas now history |
| url | https://www.aerjournal.com/articleindex/aer.2023.16 |
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