Divergent combinations of enhancers encode spatial gene expression

Divergent combinations of enhancers encode spatial gene expression

Abstract Spatial transcriptomics and epigenomics have enabled mapping gene regulation in the tissue context. However, it remains poorly understood how spatial gene expression patterns are orchestrated by enhancers. Here we build eSpatial, a computational framework that deciphers spatially resolved e...

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Bibliographic Details
Main Authors: Danni Hong, Muya Shu, Jiamao Liu, Lifang Liu, Hao Cheng, Ming Zhu, Yi Du, Bo Xu, Di Hu, Zhiyong Liu, Yannan Zhao, Jianwu Dai, Falong Lu, Jialiang Huang
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60482-1
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