Antimalarial drug resistance and population structure of Plasmodium falciparum in Mozambique using genomic surveillance at health facilities in 2021 and 2022

Antimalarial drug resistance and population structure of Plasmodium falciparum in Mozambique using genomic surveillance at health facilities in 2021 and 2022

Abstract Monitoring the emergence and spread of drug-resistant parasites is essential for effective malaria control. Here, we describe the prevalence of genetic markers of Plasmodium falciparum antimalarial drug resistance and parasite population structure in Mozambique. Drug resistance loci and mic...

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Main Authors: Simone Boene, Eduard Rovira-Vallbona, Clemente da Silva, Manuel García-Ulloa, Bernardete Rafael, Neide Canana, Andrés Aranda-Díaz, Pau Cisteró, Carla García-Fernández, Dário Tembisse, Nelo Ndimande, Arlindo Chidimatembue, Glória Matambisso, Brian Palmer, Ana Rita Chico, Mércia Dimene, Abuchahama Saifodine, José Inácio, Mariana da Silva, Mateusz Plucinski, Craig Bonnington, Flavio Wate, Eva de Carvalho, Guidion Mathe, Arnau Pujol, Beatriz Arregui-Gallego, Kiba Comiche, Abel Nhama, Lídia Nhamussua, Pedro Aide, Francisco Saute, Sónia Enosse, Bryan Greenhouse, Baltazar Candrinho, Alfredo Mayor
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Plasmodium falciparum
Malaria
Genomics
Surveillance
Drug resistance
Artemisinin
Online Access:https://doi.org/10.1038/s41598-025-02166-w
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