Intrinsic and extrinsic factors affecting the evolution of virulence in the HIV-associated opportunistic human fungal pathogen Cryptococcus neoformans

Intrinsic and extrinsic factors affecting the evolution of virulence in the HIV-associated opportunistic human fungal pathogen Cryptococcus neoformans

The fungus Cryptococcus neoformans is considered the leading cause of mortality in immunocompromised patients. While extensive research has unveiled the molecular epidemiology of C. neoformans, the influence of genetic and environmental factors on genotype–phenotype correlations remains poorly under...

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Main Authors: Yuanyuan Wang, Yiwu Yu, Jihong Liu, Linghua Li, Xiaoqing Chen, Sichu Xiong, Yuying Pan, Qinyu Tang, Munika Moses, Ping Zhan, Guojian Liao, Min Chen, Liping Zhu, Muyuan Li, Tao Zhou, Jingjun Zhao, Changbin Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
Subjects:
Cryptococcus neoformans
virulence
genotype-phenotype correlation
environmental factors
genetic variants
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2546067
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