Significance and limitations of routine p16/Ki-67 immunohistochemistry as a diagnostic tool for high-grade squamous intraepithelial lesions of the uterine cervix

Objective To evaluate the diagnostic utility and limitations of routine p16 and Ki-67 immunohistochemistry (IHC) in detecting high-grade squamous intraepithelial lesions (HSILs) in the uterine cervix. Methods We reviewed 2,061 cervical biopsy records, including 271 morphologically indeterminate squa...

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Bibliographic Details
Main Authors: Kazutaka Ozono, Fumi Kawakami, Yoshiki Mikami
Format: Article
Language:English
Published: Korean Society of Obstetrics and Gynecology 2025-01-01
Series:Obstetrics & Gynecology Science
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Online Access:http://www.ogscience.org/upload/pdf/ogs-24236.pdf
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