Construction of a multimodal esophageal cancer prognostic model with screening of key genes and investigation of their biological functions

Construction of a multimodal esophageal cancer prognostic model with screening of key genes and investigation of their biological functions

Abstract Purpose Despite decreased esophageal carcinoma incidence, its prognosis remains challenging. We aimed to develop a multimodal prognostic model to optimize treatment strategies and elucidate biological mechanisms of key regulatory genes. Methods Pivotal prognostic genes were screened using i...

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Bibliographic Details
Main Authors: Zhengsong Chang, Yiru Li, Mengyao Wang, Xin Zhang, Qiang Bai, Huan Luo, Pengyun Deng, Liping Yang, Xiaomei Li
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Esophageal cancer
CASQ2
Prognostic model
Multimodal
AKT/PI3K
Online Access:https://doi.org/10.1007/s12672-025-03404-3
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