An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A Review

The numerous applications of nanochitosan in a variety of sectors, including medicine, food, and agriculture, attract researchers to work toward the development of environmentally favorable, safe, and efficient synthesis methods. Currently, a biological approach is being developed to synthesize nano...

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Main Authors: Riki Riki, Islamudin Ahmad, Herman Herman, Arsyik Ibrahim, Arman Rusman, Erwin Samsul, Rolan Rusli, Muhammad Arifuddin, Junaidin Junaidin, Mahfuzun Bone, Hifdzur Rashif Rijai, Baso Didik Hikmawan
Format: Article
Language:English
Published: Department of Chemistry, Universitas Gadjah Mada 2025-03-01
Series:Indonesian Journal of Chemistry
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Online Access:https://jurnal.ugm.ac.id/ijc/article/view/100148
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author Riki Riki
Islamudin Ahmad
Herman Herman
Arsyik Ibrahim
Arman Rusman
Erwin Samsul
Rolan Rusli
Muhammad Arifuddin
Junaidin Junaidin
Mahfuzun Bone
Hifdzur Rashif Rijai
Baso Didik Hikmawan
author_facet Riki Riki
Islamudin Ahmad
Herman Herman
Arsyik Ibrahim
Arman Rusman
Erwin Samsul
Rolan Rusli
Muhammad Arifuddin
Junaidin Junaidin
Mahfuzun Bone
Hifdzur Rashif Rijai
Baso Didik Hikmawan
author_sort Riki Riki
collection DOAJ
description The numerous applications of nanochitosan in a variety of sectors, including medicine, food, and agriculture, attract researchers to work toward the development of environmentally favorable, safe, and efficient synthesis methods. Currently, a biological approach is being developed to synthesize nanochitosan to address the limitations of conventional methods. The synthesis of biogenic pathways employs biological entities, including plant extracts and microorganisms, as nanoparticle-forming agents. The use of extracts is more desirable due to the simple working procedure, the absence of hazardous chemicals, the economic benefits, and the use of basic equipment. This article highlights the role of biomolecules in plant extracts, including polyphenols, terpenoids, citric acid, alkaloids, and polysaccharides, in the synthesis of nanochitosan. Nanoparticle preparation protocols and characterization using zeta potential analysis techniques, scanning electron microscopy (SEM), transmission electron microscopy (TEM), UV-visible spectroscopy, and Fourier transform infrared spectroscopy (FTIR) are briefly described. The potential applications of green nanochitosan are also discussed, considering the results of biological activity testing and the potential mechanisms associated with these activities. According to the results of numerous studies highlighted in this review, nanochitosan synthesis utilizing plant extracts appears to be a promising alternative approach to conventional methods.
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institution OA Journals
issn 1411-9420
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language English
publishDate 2025-03-01
publisher Department of Chemistry, Universitas Gadjah Mada
record_format Article
series Indonesian Journal of Chemistry
spelling doaj-art-112674e056cb42fcb9e7188bfcb4e1172025-08-20T02:26:31ZengDepartment of Chemistry, Universitas Gadjah MadaIndonesian Journal of Chemistry1411-94202460-15782025-03-0125263865410.22146/ijc.10014837132An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A ReviewRiki Riki0Islamudin Ahmad1Herman Herman2Arsyik Ibrahim3Arman Rusman4Erwin Samsul5Rolan Rusli6Muhammad Arifuddin7Junaidin Junaidin8Mahfuzun Bone9Hifdzur Rashif Rijai10Baso Didik Hikmawan11Pharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaPharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda 75119, IndonesiaThe numerous applications of nanochitosan in a variety of sectors, including medicine, food, and agriculture, attract researchers to work toward the development of environmentally favorable, safe, and efficient synthesis methods. Currently, a biological approach is being developed to synthesize nanochitosan to address the limitations of conventional methods. The synthesis of biogenic pathways employs biological entities, including plant extracts and microorganisms, as nanoparticle-forming agents. The use of extracts is more desirable due to the simple working procedure, the absence of hazardous chemicals, the economic benefits, and the use of basic equipment. This article highlights the role of biomolecules in plant extracts, including polyphenols, terpenoids, citric acid, alkaloids, and polysaccharides, in the synthesis of nanochitosan. Nanoparticle preparation protocols and characterization using zeta potential analysis techniques, scanning electron microscopy (SEM), transmission electron microscopy (TEM), UV-visible spectroscopy, and Fourier transform infrared spectroscopy (FTIR) are briefly described. The potential applications of green nanochitosan are also discussed, considering the results of biological activity testing and the potential mechanisms associated with these activities. According to the results of numerous studies highlighted in this review, nanochitosan synthesis utilizing plant extracts appears to be a promising alternative approach to conventional methods.https://jurnal.ugm.ac.id/ijc/article/view/100148chitosanforming agentsgreen chemistrynanoparticlesbioactivity
spellingShingle Riki Riki
Islamudin Ahmad
Herman Herman
Arsyik Ibrahim
Arman Rusman
Erwin Samsul
Rolan Rusli
Muhammad Arifuddin
Junaidin Junaidin
Mahfuzun Bone
Hifdzur Rashif Rijai
Baso Didik Hikmawan
An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A Review
Indonesian Journal of Chemistry
chitosan
forming agents
green chemistry
nanoparticles
bioactivity
title An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A Review
title_full An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A Review
title_fullStr An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A Review
title_full_unstemmed An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A Review
title_short An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A Review
title_sort innovative strategy for the green synthesis of nanochitosan using plant extracts and their possible applications a review
topic chitosan
forming agents
green chemistry
nanoparticles
bioactivity
url https://jurnal.ugm.ac.id/ijc/article/view/100148
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