Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism

Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism

BackgroundAtherosclerosis is a widely studied pathophysiological foundation of cardiovascular diseases. Inflammation and dyslipidemia are risk factors that promote the formation of atherosclerotic plaques. The gut microbiota and their metabolites are considered independent risk factors for atheroscl...

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Bibliographic Details
Main Authors: Dan Li, Yujuan Li, Shengjie Yang, Xiaonan Zhang, Yu Cao, Ran Zhao, Yixi Zhao, Xiao Jin, Jing Lu, Xinyue Wang, Qiutao Wang, Longtao Liu, Min Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
atherosclerosis
gut microbiota
TMAO
polydatin
hawthorn flavonoids
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1515485/full
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