Highest Recorded Serum Creatinine

Serum creatinine is a commonly used laboratory marker to assess kidney function; however, there has not been an established level of serum creatinine to predict mortality. After extensive literature review, we present a case of the highest recorded serum creatinine of 73.8 mg/dL in a 23-year-old mal...

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Main Authors: Christine Persaud, Uttsav Sandesara, Victor Hoang, Joshua Tate, Wayne Latack, David Dado
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2021/6048919
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author Christine Persaud
Uttsav Sandesara
Victor Hoang
Joshua Tate
Wayne Latack
David Dado
author_facet Christine Persaud
Uttsav Sandesara
Victor Hoang
Joshua Tate
Wayne Latack
David Dado
author_sort Christine Persaud
collection DOAJ
description Serum creatinine is a commonly used laboratory marker to assess kidney function; however, there has not been an established level of serum creatinine to predict mortality. After extensive literature review, we present a case of the highest recorded serum creatinine of 73.8 mg/dL in a 23-year-old male with the history of pediatric deceased donor kidney transplant (DDKT). He initially presented with uremia and signs of acute renal allograft failure after two months of immunosuppressive medication nonadherence, ultimately requiring emergent hemodialysis, which was complicated by new onset seizures. This was the patient’s fourth episode of late acute rejection and emphasizes the need for education of immunosuppressant adherence and periodic monitoring of renal function in high-risk patients. Though there is no known creatinine level incompatible with life, this patient appears to have the highest known serum creatinine in a uremic patient on record.
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series Case Reports in Nephrology
spelling doaj-art-1121787a62334b59badb629a52188dc72025-02-03T07:24:22ZengWileyCase Reports in Nephrology2090-66412090-665X2021-01-01202110.1155/2021/60489196048919Highest Recorded Serum CreatinineChristine Persaud0Uttsav Sandesara1Victor Hoang2Joshua Tate3Wayne Latack4David Dado5Department of Medicine, Keesler Medical Center, Biloxi 39534, MS, USADepartment of Medicine, University of Mississippi Medical Center, Jackson 39216, MS, USADepartment of Medicine, Keesler Medical Center, Biloxi 39534, MS, USADepartment of Medicine, Keesler Medical Center, Biloxi 39534, MS, USADepartment of Medicine, Keesler Medical Center, Biloxi 39534, MS, USADepartment of Medicine, Keesler Medical Center, Biloxi 39534, MS, USASerum creatinine is a commonly used laboratory marker to assess kidney function; however, there has not been an established level of serum creatinine to predict mortality. After extensive literature review, we present a case of the highest recorded serum creatinine of 73.8 mg/dL in a 23-year-old male with the history of pediatric deceased donor kidney transplant (DDKT). He initially presented with uremia and signs of acute renal allograft failure after two months of immunosuppressive medication nonadherence, ultimately requiring emergent hemodialysis, which was complicated by new onset seizures. This was the patient’s fourth episode of late acute rejection and emphasizes the need for education of immunosuppressant adherence and periodic monitoring of renal function in high-risk patients. Though there is no known creatinine level incompatible with life, this patient appears to have the highest known serum creatinine in a uremic patient on record.http://dx.doi.org/10.1155/2021/6048919
spellingShingle Christine Persaud
Uttsav Sandesara
Victor Hoang
Joshua Tate
Wayne Latack
David Dado
Highest Recorded Serum Creatinine
Case Reports in Nephrology
title Highest Recorded Serum Creatinine
title_full Highest Recorded Serum Creatinine
title_fullStr Highest Recorded Serum Creatinine
title_full_unstemmed Highest Recorded Serum Creatinine
title_short Highest Recorded Serum Creatinine
title_sort highest recorded serum creatinine
url http://dx.doi.org/10.1155/2021/6048919
work_keys_str_mv AT christinepersaud highestrecordedserumcreatinine
AT uttsavsandesara highestrecordedserumcreatinine
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AT joshuatate highestrecordedserumcreatinine
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AT daviddado highestrecordedserumcreatinine