Drugs and other substances aggravating acne vulgaris

Introduction and Purpose This review explores several factors exacerbating acne, including the supplementation of vitamins B6 and B12, the impact of red ginseng oil, dairy and whey product consumption, iodine association, anabolic-androgenic steroids, alcohol abuse, and the influence of progest...

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Main Authors: Karolina Zalewa, Joanna Olszak, Wojciech Kapłan, Dominika Orłowska, Lidia Bartoszek
Format: Article
Language:English
Published: Kazimierz Wielki University 2024-10-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/55774
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author Karolina Zalewa
Joanna Olszak
Wojciech Kapłan
Dominika Orłowska
Lidia Bartoszek
author_facet Karolina Zalewa
Joanna Olszak
Wojciech Kapłan
Dominika Orłowska
Lidia Bartoszek
author_sort Karolina Zalewa
collection DOAJ
description Introduction and Purpose This review explores several factors exacerbating acne, including the supplementation of vitamins B6 and B12, the impact of red ginseng oil, dairy and whey product consumption, iodine association, anabolic-androgenic steroids, alcohol abuse, and the influence of progestin contraceptives. Material and methods This review is based on articles from the PubMed database, covering the years 2018-2023, using keywords: acne vulgaris, acne vulgaris aggravation, substances aggravating acne vulgaris. Results High doses of B6 and B12 have been reported to worsen acne, potentially linked to their prolonged use. Red ginseng oil, believed to have numerous health benefits, may exacerbate acne symptoms by increasing inflammatory biomarkers. Dairy consumption, specifically casein and whey proteins, is associated with increased insulin-like growth factor 1, contributing to acne aggravation. Iodine has been extensively linked to acneiform eruptions, and its correlation with dairy consumption is hypothesized. Anabolic-androgenic steroids, found in muscle-building supplements, elevate sebum production and may cause acne fulminans. Alcohol abuse further intensifies acne symptoms by impacting testosterone levels, promoting proinflammatory cytokine production, and altering the skin microbiome. Progestin contraceptives, particularly levonorgestrel and etonorgestrel, exhibit androgenic properties that may increase sebum production and potentially aggravate acne. Conclusions Understanding and identifying these exacerbating factors are crucial for healthcare providers to enhance anti-acne therapy outcomes, emphasizing the importance of not only treating but also preventing the escalation of acne manifestations in patients.
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spelling doaj-art-1111d75d7606488389acce8c8cf2615a2025-08-20T02:18:15ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062024-10-017010.12775/JEHS.2024.70.55774Drugs and other substances aggravating acne vulgarisKarolina Zalewa0Joanna Olszak1Wojciech Kapłan2Dominika Orłowska3Lidia Bartoszek4Medical University of WarsawIndependent Public Hospital No. 4 in Lublin, Jaczewskiego street 8, 20-954 Lublin, PolandChair and Department of Psychology, Medical University of Lublin, Chodźki street 7, 20-093 Lublin, PolandTrauma Surgery Hospital of St. Anna, Barska street 16/20, 02-315 Warsaw, Poland National Medical Institute of the Ministry of the Interior and Administration, Wołoska street 137, 02-507 Warsaw, Poland Introduction and Purpose This review explores several factors exacerbating acne, including the supplementation of vitamins B6 and B12, the impact of red ginseng oil, dairy and whey product consumption, iodine association, anabolic-androgenic steroids, alcohol abuse, and the influence of progestin contraceptives. Material and methods This review is based on articles from the PubMed database, covering the years 2018-2023, using keywords: acne vulgaris, acne vulgaris aggravation, substances aggravating acne vulgaris. Results High doses of B6 and B12 have been reported to worsen acne, potentially linked to their prolonged use. Red ginseng oil, believed to have numerous health benefits, may exacerbate acne symptoms by increasing inflammatory biomarkers. Dairy consumption, specifically casein and whey proteins, is associated with increased insulin-like growth factor 1, contributing to acne aggravation. Iodine has been extensively linked to acneiform eruptions, and its correlation with dairy consumption is hypothesized. Anabolic-androgenic steroids, found in muscle-building supplements, elevate sebum production and may cause acne fulminans. Alcohol abuse further intensifies acne symptoms by impacting testosterone levels, promoting proinflammatory cytokine production, and altering the skin microbiome. Progestin contraceptives, particularly levonorgestrel and etonorgestrel, exhibit androgenic properties that may increase sebum production and potentially aggravate acne. Conclusions Understanding and identifying these exacerbating factors are crucial for healthcare providers to enhance anti-acne therapy outcomes, emphasizing the importance of not only treating but also preventing the escalation of acne manifestations in patients. https://apcz.umk.pl/JEHS/article/view/55774acne vulgarisacne
spellingShingle Karolina Zalewa
Joanna Olszak
Wojciech Kapłan
Dominika Orłowska
Lidia Bartoszek
Drugs and other substances aggravating acne vulgaris
Journal of Education, Health and Sport
acne vulgaris
acne
title Drugs and other substances aggravating acne vulgaris
title_full Drugs and other substances aggravating acne vulgaris
title_fullStr Drugs and other substances aggravating acne vulgaris
title_full_unstemmed Drugs and other substances aggravating acne vulgaris
title_short Drugs and other substances aggravating acne vulgaris
title_sort drugs and other substances aggravating acne vulgaris
topic acne vulgaris
acne
url https://apcz.umk.pl/JEHS/article/view/55774
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AT joannaolszak drugsandothersubstancesaggravatingacnevulgaris
AT wojciechkapłan drugsandothersubstancesaggravatingacnevulgaris
AT dominikaorłowska drugsandothersubstancesaggravatingacnevulgaris
AT lidiabartoszek drugsandothersubstancesaggravatingacnevulgaris