Reversible Nephropathy Associated with Jet Fuel Exposure
Acute kidney injury (AKI) with progression to oliguric or anuric acute renal failure (ARF) is often related to use of well-known nephrotoxic agents including medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), angiotensin-converting enzyme inhibitors (ACEis)/angiotensin II receptor bl...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2020/2932415 |
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| author | Latif A. Salam Khabbab Amin Regina Cheng Noriyuki Murakami Clinton Brown Lawrence Kwon |
| author_facet | Latif A. Salam Khabbab Amin Regina Cheng Noriyuki Murakami Clinton Brown Lawrence Kwon |
| author_sort | Latif A. Salam |
| collection | DOAJ |
| description | Acute kidney injury (AKI) with progression to oliguric or anuric acute renal failure (ARF) is often related to use of well-known nephrotoxic agents including medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), angiotensin-converting enzyme inhibitors (ACEis)/angiotensin II receptor blockers (ARBs), and certain classes of antibiotics. Hyperosmolar IV contrast is also a well-known nephrotoxic agent. Severe sepsis with subsequent hypotension, marked hyperglycemia, and those with difficulty accessing water or with poor oral intake can also present with acute kidney injury related to kidney hypoperfusion, dehydration, and volume depletion. In this case report, we discover and discuss the possible effects of regular and daily occupational exposure of jet fuel (a mixture of hydrocarbons) on renal function. Jet fuel is an underdescribed and not well-known nephrotoxic agent; however, its direct toxicity on kidney function appears to be reversible with removal of exposure and aggressive fluid hydration. |
| format | Article |
| id | doaj-art-1110fcd288e64873b52512a9d5c28421 |
| institution | OA Journals |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-1110fcd288e64873b52512a9d5c284212025-08-20T02:02:19ZengWileyCase Reports in Nephrology2090-66412090-665X2020-01-01202010.1155/2020/29324152932415Reversible Nephropathy Associated with Jet Fuel ExposureLatif A. Salam0Khabbab Amin1Regina Cheng2Noriyuki Murakami3Clinton Brown4Lawrence Kwon5Department of Internal Medicine, Section of Hospital Medicine, State University of New York (SUNY) Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USADepartment of Internal Medicine, Section of Hospital Medicine, State University of New York (SUNY) Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USADepartment of Internal Medicine, Section of Hospital Medicine, State University of New York (SUNY) Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USADepartment of Internal Medicine, Section of Hospital Medicine, State University of New York (SUNY) Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USABrooklyn Health Disparities Center, Division of Nephrology, State University of New York (SUNY) Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USADepartment of Internal Medicine, Division of Nephrology, State University of New York (SUNY) Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USAAcute kidney injury (AKI) with progression to oliguric or anuric acute renal failure (ARF) is often related to use of well-known nephrotoxic agents including medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), angiotensin-converting enzyme inhibitors (ACEis)/angiotensin II receptor blockers (ARBs), and certain classes of antibiotics. Hyperosmolar IV contrast is also a well-known nephrotoxic agent. Severe sepsis with subsequent hypotension, marked hyperglycemia, and those with difficulty accessing water or with poor oral intake can also present with acute kidney injury related to kidney hypoperfusion, dehydration, and volume depletion. In this case report, we discover and discuss the possible effects of regular and daily occupational exposure of jet fuel (a mixture of hydrocarbons) on renal function. Jet fuel is an underdescribed and not well-known nephrotoxic agent; however, its direct toxicity on kidney function appears to be reversible with removal of exposure and aggressive fluid hydration.http://dx.doi.org/10.1155/2020/2932415 |
| spellingShingle | Latif A. Salam Khabbab Amin Regina Cheng Noriyuki Murakami Clinton Brown Lawrence Kwon Reversible Nephropathy Associated with Jet Fuel Exposure Case Reports in Nephrology |
| title | Reversible Nephropathy Associated with Jet Fuel Exposure |
| title_full | Reversible Nephropathy Associated with Jet Fuel Exposure |
| title_fullStr | Reversible Nephropathy Associated with Jet Fuel Exposure |
| title_full_unstemmed | Reversible Nephropathy Associated with Jet Fuel Exposure |
| title_short | Reversible Nephropathy Associated with Jet Fuel Exposure |
| title_sort | reversible nephropathy associated with jet fuel exposure |
| url | http://dx.doi.org/10.1155/2020/2932415 |
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