RISK OF RECURRENT THROMBOTIC EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME AND HIGH PLASMA LEVELS OF D-DIMER

Aim. To study the association of plasma D-dimer levels and the risk of thrombotic events in patients hospitalised with acute coronary syndrome (ACS).Material and methods. The study included 70 patients, aged 34-88 years, who were admitted to the Acute Coronary Care Unit with the ACS diagnosis.Result...

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Main Authors: A. V. Panina, N. F. Puchinyan, Ya. P. Dovgalevskyi, N. V. Furman, P. V. Dolotovskaya, L. I. Malinova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2013-08-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/209
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author A. V. Panina
N. F. Puchinyan
Ya. P. Dovgalevskyi
N. V. Furman
P. V. Dolotovskaya
L. I. Malinova
author_facet A. V. Panina
N. F. Puchinyan
Ya. P. Dovgalevskyi
N. V. Furman
P. V. Dolotovskaya
L. I. Malinova
author_sort A. V. Panina
collection DOAJ
description Aim. To study the association of plasma D-dimer levels and the risk of thrombotic events in patients hospitalised with acute coronary syndrome (ACS).Material and methods. The study included 70 patients, aged 34-88 years, who were admitted to the Acute Coronary Care Unit with the ACS diagnosis.Results. During the follow-up period, thrombotic events were registered in 12 patients (17%). Three patients with myocardial infarction (MI) suffered recurrent MI. Nine patients were rehospitalised with the unstable angina (UA) diagnosis. All participants were divided into quartiles by the levels of D-dimer (25% percentile 136 ng/ml; median 1250 ng/ml; and 75% percentile 2930 ng/ml). High plasma levels of D-dimer (third quartile) were associated with a 1,5-fold increase in the risk of recurrent thrombotic events among ACS patients.Conclusion. In ACS patients, plasma D-dimer levels could be regarded as one of the additional risk factors of thrombotic events.
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issn 1728-8800
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publishDate 2013-08-01
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record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-110cb4648b294cf79955b5183bb00e1c2025-08-20T02:59:54Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252013-08-01124263110.15829/1728-8800-2013-4-26-31209RISK OF RECURRENT THROMBOTIC EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME AND HIGH PLASMA LEVELS OF D-DIMERA. V. Panina0N. F. Puchinyan1Ya. P. Dovgalevskyi2N. V. Furman3P. V. Dolotovskaya4L. I. Malinova5Saratov Research Institute of CardiologySaratov Research Institute of CardiologyV.I. Razumovskyi Saratov State Medical University, SaratovSaratov Research Institute of CardiologySaratov Research Institute of CardiologySaratov Research Institute of CardiologyAim. To study the association of plasma D-dimer levels and the risk of thrombotic events in patients hospitalised with acute coronary syndrome (ACS).Material and methods. The study included 70 patients, aged 34-88 years, who were admitted to the Acute Coronary Care Unit with the ACS diagnosis.Results. During the follow-up period, thrombotic events were registered in 12 patients (17%). Three patients with myocardial infarction (MI) suffered recurrent MI. Nine patients were rehospitalised with the unstable angina (UA) diagnosis. All participants were divided into quartiles by the levels of D-dimer (25% percentile 136 ng/ml; median 1250 ng/ml; and 75% percentile 2930 ng/ml). High plasma levels of D-dimer (third quartile) were associated with a 1,5-fold increase in the risk of recurrent thrombotic events among ACS patients.Conclusion. In ACS patients, plasma D-dimer levels could be regarded as one of the additional risk factors of thrombotic events.https://cardiovascular.elpub.ru/jour/article/view/209coronary heart diseaseatherothrombosisd-dimerhigh coronary risk
spellingShingle A. V. Panina
N. F. Puchinyan
Ya. P. Dovgalevskyi
N. V. Furman
P. V. Dolotovskaya
L. I. Malinova
RISK OF RECURRENT THROMBOTIC EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME AND HIGH PLASMA LEVELS OF D-DIMER
Кардиоваскулярная терапия и профилактика
coronary heart disease
atherothrombosis
d-dimer
high coronary risk
title RISK OF RECURRENT THROMBOTIC EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME AND HIGH PLASMA LEVELS OF D-DIMER
title_full RISK OF RECURRENT THROMBOTIC EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME AND HIGH PLASMA LEVELS OF D-DIMER
title_fullStr RISK OF RECURRENT THROMBOTIC EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME AND HIGH PLASMA LEVELS OF D-DIMER
title_full_unstemmed RISK OF RECURRENT THROMBOTIC EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME AND HIGH PLASMA LEVELS OF D-DIMER
title_short RISK OF RECURRENT THROMBOTIC EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME AND HIGH PLASMA LEVELS OF D-DIMER
title_sort risk of recurrent thrombotic events in patients with acute coronary syndrome and high plasma levels of d dimer
topic coronary heart disease
atherothrombosis
d-dimer
high coronary risk
url https://cardiovascular.elpub.ru/jour/article/view/209
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