P4HB maintains Wnt-dependent stemness in glioblastoma stem cells as a precision therapeutic target and serum marker

P4HB maintains Wnt-dependent stemness in glioblastoma stem cells as a precision therapeutic target and serum marker

Abstract Glioblastoma stem cells (GSCs) are pivotal in the recurrence and drug resistance of glioblastoma multiforme (GBM). However, precision therapeutic and diagnostic markers for GSCs have not been fully established. Here, using bioinformatics and experimental analysis, we identified P4HB, a prot...

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Bibliographic Details
Main Authors: Zheng Yuan, Hongbo Jing, Yilin Deng, Meichen Liu, Tao Jiang, Xiong Jin, Weiwei Lin, Yang Liu, Jinlong Yin
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-024-00541-2
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