Identification of ligand and receptor interactions in CKD and MASH through the integration of single cell and spatial transcriptomics.
<h4>Background</h4>Chronic Kidney Disease (CKD) and Metabolic dysfunction-associated steatohepatitis (MASH) are metabolic fibroinflammatory diseases. Combining single-cell (scRNAseq) and spatial transcriptomics (ST) could give unprecedented molecular disease understanding at single-cell...
Saved in:
| Main Authors: | Jaime Moreno, Lise Lotte Gluud, Elisabeth D Galsgaard, Henning Hvid, Gianluca Mazzoni, Vivek Das |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0302853&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Comparative Analysis of the Human Proteome Profile in Visceral Adipose and Liver Tissue in Individuals with Obesity with and Without MASLD and MASH
by: Julie S. Pedersen, et al.
Published: (2025-04-01) -
Female glucagon receptor knockout mice are prone to steatosis but resistant to weight gain when fed a MASH‐promoting GAN diet and a high‐fat diet
by: Katrine D. Galsgaard, et al.
Published: (2025-02-01) -
Single-cell transcriptome reveals the reprogramming of immune microenvironment during the transition from MASH to HCC
by: Yu Huang, et al.
Published: (2025-06-01) -
Transcriptomics, lipidomics, and single-nucleus RNA sequencing integration: exploring sphingolipids in MASH-HCC progression
by: Jing Zeng, et al.
Published: (2025-03-01) -
Multifaceted Interactions Between Bile Acids, Their Receptors, and MASH: From Molecular Mechanisms to Clinical Therapeutics
by: Xuan Tang, et al.
Published: (2025-07-01)