Quantification of transplant-derived circulating cell-free DNA in absence of a donor genotype.

Quantification of transplant-derived circulating cell-free DNA in absence of a donor genotype.

Quantification of cell-free DNA (cfDNA) in circulating blood derived from a transplanted organ is a powerful approach to monitoring post-transplant injury. Genome transplant dynamics (GTD) quantifies donor-derived cfDNA (dd-cfDNA) by taking advantage of single-nucleotide polymorphisms (SNPs) distrib...

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Bibliographic Details
Main Authors: Eilon Sharon, Hao Shi, Sandhya Kharbanda, Winston Koh, Lance R Martin, Kiran K Khush, Hannah Valantine, Jonathan K Pritchard, Iwijn De Vlaminck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005629&type=printable
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