Low intensity pulsed ultrasound alleviates synovial fibrosis in osteoarthritis via the PI3K/AKT pathway

Low intensity pulsed ultrasound alleviates synovial fibrosis in osteoarthritis via the PI3K/AKT pathway

Abstract Previous studies have reported that low-intensity pulsed ultrasound (LIPUS) can alleviate cartilage degradation in osteoarthritis (OA). However, the functions and mechanisms of LIPUS in synovial fibrosis with OA require further study. To investigate the role of the PI3K/AKT signaling pathwa...

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Bibliographic Details
Main Authors: Qing Liao, Jun Chen, Gang Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Osteoarthritis
Synovial fibrosis
Low-intensity pulsed ultrasound
PI3K/AKT signaling pathway
Synovitis
Fibroblast-like synoviocyte
Online Access:https://doi.org/10.1038/s41598-025-92413-x
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