The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy
Immune checkpoint inhibitors (ICIs) therapy has recently been introduced to all kinds of cancers. The adverse reactions associated with this therapy have attracted much attention. The heart-related adverse reactions are mainly the immune-related myocarditis and heart failure. Cases of adverse cardia...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/8367651 |
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| _version_ | 1849304342183542784 |
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| author | Fangning Rong Kangting Ji Yingpei Weng Yangpei Peng |
| author_facet | Fangning Rong Kangting Ji Yingpei Weng Yangpei Peng |
| author_sort | Fangning Rong |
| collection | DOAJ |
| description | Immune checkpoint inhibitors (ICIs) therapy has recently been introduced to all kinds of cancers. The adverse reactions associated with this therapy have attracted much attention. The heart-related adverse reactions are mainly the immune-related myocarditis and heart failure. Cases of adverse cardiac reactions caused by ICIs therapy have been clearly reported. However, the pathogenesis of the adverse cardiac reactions remains unclear. Therefore, this article briefly reviews the mechanism and management of adverse cardiac reactions caused by ICIs therapy. |
| format | Article |
| id | doaj-art-10eb91be1966483987f5edeb94741c41 |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-10eb91be1966483987f5edeb94741c412025-08-20T03:55:45ZengWileyCardiology Research and Practice2090-80162090-05972020-01-01202010.1155/2020/83676518367651The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors TherapyFangning Rong0Kangting Ji1Yingpei Weng2Yangpei Peng3The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, ChinaThe Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, ChinaThe Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, ChinaThe Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, ChinaImmune checkpoint inhibitors (ICIs) therapy has recently been introduced to all kinds of cancers. The adverse reactions associated with this therapy have attracted much attention. The heart-related adverse reactions are mainly the immune-related myocarditis and heart failure. Cases of adverse cardiac reactions caused by ICIs therapy have been clearly reported. However, the pathogenesis of the adverse cardiac reactions remains unclear. Therefore, this article briefly reviews the mechanism and management of adverse cardiac reactions caused by ICIs therapy.http://dx.doi.org/10.1155/2020/8367651 |
| spellingShingle | Fangning Rong Kangting Ji Yingpei Weng Yangpei Peng The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy Cardiology Research and Practice |
| title | The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy |
| title_full | The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy |
| title_fullStr | The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy |
| title_full_unstemmed | The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy |
| title_short | The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy |
| title_sort | mechanism and management of adverse cardiac reactions induced by immune checkpoint inhibitors therapy |
| url | http://dx.doi.org/10.1155/2020/8367651 |
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