Synthesis, Physical Characterization and In Silico Study of Novel Schiff Base
Now a days treatment of infectious diseases is a challenging issue faced by the medical community. There are bunch of marketed drugs held modified pharmacological and toxicological properties and probably Schiff bases are versatile C=N (Imine) containing compounds possessing broad spectrum of b...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Krupanidhi College of Pharmacy
2025-03-01
|
| Series: | Journal of Pharmaceutical Research |
| Online Access: | https://jopcr.com/articles/synthesis-physical-characterization-and-in-silico-study-of-novel-schiff-base |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Now a days treatment of infectious diseases is a challenging issue faced by the medical community. There are bunch of marketed drugs held modified pharmacological and toxicological properties and probably Schiff bases are versatile C=N (Imine) containing compounds possessing broad spectrum of biological activity and showed some degree of antibacterial, cytotoxic effects, antifungal, and antimalarial. In this research work a novel SB’s derivative has been designed, synthesized by using green method, and evaluated to explore physical characterization such as purity assessment of synthesized product by using TLC technique, spectral analysis by using IR spectroscopy, melting point determination by conventional method, molecular docking by using various computerized software, solubility determination by using various polar and non-polar solvent. The aim behind this research is to focus on green synthetic procedure used in the synthesis of novel Schiff bases, physical characterization and in silico study to find the most efficient method to get high yield in lesser time along with environment friendly.
Keywords: Synthesis, Evaluation, Spectral Analysis, ADMET prediction, Molecular Docking |
|---|---|
| ISSN: | 0973-7200 2454-8405 |