Organophosphate Esters and Polybrominated Diphenyl Ethers in Vehicle Dust: Concentrations, Sources, and Health Risk Assessment

Background: The primary flame retardants in vehicles, organophosphates (OPEs) and polybrominated diphenyl ethers (PBDEs), volatilize and accumulate in the enclosed vehicle environment, posing potential health risks. Amidst the rising number of vehicles, the scrutiny of persistent organic pollutants...

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Main Authors: Junji Wang, Jianzai Lin, Xi Zhang, Qinghong Zeng, Zhu Zhu, Siyuan Zhao, Deyan Cao, Meilin Zhu
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Toxics
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Online Access:https://www.mdpi.com/2305-6304/12/11/806
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author Junji Wang
Jianzai Lin
Xi Zhang
Qinghong Zeng
Zhu Zhu
Siyuan Zhao
Deyan Cao
Meilin Zhu
author_facet Junji Wang
Jianzai Lin
Xi Zhang
Qinghong Zeng
Zhu Zhu
Siyuan Zhao
Deyan Cao
Meilin Zhu
author_sort Junji Wang
collection DOAJ
description Background: The primary flame retardants in vehicles, organophosphates (OPEs) and polybrominated diphenyl ethers (PBDEs), volatilize and accumulate in the enclosed vehicle environment, posing potential health risks. Amidst the rising number of vehicles, the scrutiny of persistent organic pollutants like OPEs and PBDEs in vehicles is increasing. This study investigates occupational and nonoccupational population exposure to specific OPEs (TnBP, TBOEP, TEHP, TCEP, TCiPP, TDCiPP, TPhP, EHDPP) and PBDEs (BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154, BDE-183, BDE-209) in vehicle dust. Methods: Data on OPEs and PBDEs in vehicle dust were sourced from PubMed and Web of Science. We applied PCA and PMF to identify pollutant sources and assessed health risks using the hazard index (HI) and carcinogenic risk (CR) methods. Monte Carlo simulations were conducted for uncertainty analysis, evaluating variable contributions to the results. Results: The predominant OPE in dust samples was TDCiPP (mean value: 4.34 × 10<sup>4</sup> ng g<sup>−1</sup>), and the main PBDE was BDE-209 (mean value: 1.52 × 10<sup>4</sup> ng g<sup>−1</sup>). Potential sources of OPEs in vehicle dust include polyvinyl chloride (PVC) upholstery, polyurethane foam (PUF) seats, electronics, carpet wear, hydraulic oil, and plastic wear in the brake system. PBDE sources likely include automotive parts, PVC upholstery, seats, carpets, and electronics. The 90th percentile HI and CR values for occupational and nonoccupational populations exposed to OPEs and PBDEs indicate that the noncarcinogenic and carcinogenic risks are relatively low. A sensitivity analysis showed that the pollutant concentration, time in the vehicle, exposure frequency, and duration significantly influence health risks. Conclusions: The health risks to both occupational and nonoccupational populations from exposure to OPEs and PBDEs in vehicle dust are relatively low.
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spelling doaj-art-10d17541faa647fa8d5105d782347f402025-08-20T01:53:56ZengMDPI AGToxics2305-63042024-11-01121180610.3390/toxics12110806Organophosphate Esters and Polybrominated Diphenyl Ethers in Vehicle Dust: Concentrations, Sources, and Health Risk AssessmentJunji Wang0Jianzai Lin1Xi Zhang2Qinghong Zeng3Zhu Zhu4Siyuan Zhao5Deyan Cao6Meilin Zhu7School of Public Health, Ningxia Medical University, Yinchuan 750004, ChinaSchool of Public Health, Ningxia Medical University, Yinchuan 750004, ChinaSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, ChinaSchool of Public Health, Ningxia Medical University, Yinchuan 750004, ChinaSchool of Public Health, Ningxia Medical University, Yinchuan 750004, ChinaSchool of Public Health, Ningxia Medical University, Yinchuan 750004, ChinaSchool of Public Health, Ningxia Medical University, Yinchuan 750004, ChinaSchool of Public Health, Ningxia Medical University, Yinchuan 750004, ChinaBackground: The primary flame retardants in vehicles, organophosphates (OPEs) and polybrominated diphenyl ethers (PBDEs), volatilize and accumulate in the enclosed vehicle environment, posing potential health risks. Amidst the rising number of vehicles, the scrutiny of persistent organic pollutants like OPEs and PBDEs in vehicles is increasing. This study investigates occupational and nonoccupational population exposure to specific OPEs (TnBP, TBOEP, TEHP, TCEP, TCiPP, TDCiPP, TPhP, EHDPP) and PBDEs (BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154, BDE-183, BDE-209) in vehicle dust. Methods: Data on OPEs and PBDEs in vehicle dust were sourced from PubMed and Web of Science. We applied PCA and PMF to identify pollutant sources and assessed health risks using the hazard index (HI) and carcinogenic risk (CR) methods. Monte Carlo simulations were conducted for uncertainty analysis, evaluating variable contributions to the results. Results: The predominant OPE in dust samples was TDCiPP (mean value: 4.34 × 10<sup>4</sup> ng g<sup>−1</sup>), and the main PBDE was BDE-209 (mean value: 1.52 × 10<sup>4</sup> ng g<sup>−1</sup>). Potential sources of OPEs in vehicle dust include polyvinyl chloride (PVC) upholstery, polyurethane foam (PUF) seats, electronics, carpet wear, hydraulic oil, and plastic wear in the brake system. PBDE sources likely include automotive parts, PVC upholstery, seats, carpets, and electronics. The 90th percentile HI and CR values for occupational and nonoccupational populations exposed to OPEs and PBDEs indicate that the noncarcinogenic and carcinogenic risks are relatively low. A sensitivity analysis showed that the pollutant concentration, time in the vehicle, exposure frequency, and duration significantly influence health risks. Conclusions: The health risks to both occupational and nonoccupational populations from exposure to OPEs and PBDEs in vehicle dust are relatively low.https://www.mdpi.com/2305-6304/12/11/806vehicle dustorganophosphate esters and polybrominated diphenyl ethersPCAPMFhealth risk assessmentMonte Carlo simulation
spellingShingle Junji Wang
Jianzai Lin
Xi Zhang
Qinghong Zeng
Zhu Zhu
Siyuan Zhao
Deyan Cao
Meilin Zhu
Organophosphate Esters and Polybrominated Diphenyl Ethers in Vehicle Dust: Concentrations, Sources, and Health Risk Assessment
Toxics
vehicle dust
organophosphate esters and polybrominated diphenyl ethers
PCA
PMF
health risk assessment
Monte Carlo simulation
title Organophosphate Esters and Polybrominated Diphenyl Ethers in Vehicle Dust: Concentrations, Sources, and Health Risk Assessment
title_full Organophosphate Esters and Polybrominated Diphenyl Ethers in Vehicle Dust: Concentrations, Sources, and Health Risk Assessment
title_fullStr Organophosphate Esters and Polybrominated Diphenyl Ethers in Vehicle Dust: Concentrations, Sources, and Health Risk Assessment
title_full_unstemmed Organophosphate Esters and Polybrominated Diphenyl Ethers in Vehicle Dust: Concentrations, Sources, and Health Risk Assessment
title_short Organophosphate Esters and Polybrominated Diphenyl Ethers in Vehicle Dust: Concentrations, Sources, and Health Risk Assessment
title_sort organophosphate esters and polybrominated diphenyl ethers in vehicle dust concentrations sources and health risk assessment
topic vehicle dust
organophosphate esters and polybrominated diphenyl ethers
PCA
PMF
health risk assessment
Monte Carlo simulation
url https://www.mdpi.com/2305-6304/12/11/806
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