Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment
Postinfectious IBS is defined in the industrialized world as IBS onset following a sentinel gastrointestinal infection. In developing nations, where repeated bacterial and parasitic gastrointestinal infections are common, the IBS pathophysiology may be altered. Our aim was to investigate the relatio...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/343812 |
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| author | Douglas R. Morgan Matthew Benshoff Mercedes Cáceres Sylvia Becker-Dreps Loreto Cortes Christopher F. Martin Max Schmulson Rodolfo Peña |
| author_facet | Douglas R. Morgan Matthew Benshoff Mercedes Cáceres Sylvia Becker-Dreps Loreto Cortes Christopher F. Martin Max Schmulson Rodolfo Peña |
| author_sort | Douglas R. Morgan |
| collection | DOAJ |
| description | Postinfectious IBS is defined in the industrialized world as IBS onset following a sentinel gastrointestinal infection. In developing nations, where repeated bacterial and parasitic gastrointestinal infections are common, the IBS pathophysiology may be altered. Our aim was to investigate the relationship between intestinal parasite infection and IBS in the “nonsterile” developing world environment. IBS subjects were identified from a population-based sample of 1624 participants using the Rome II Modular Questionnaire. Stool samples from cases and randomly selected controls were examined for ova and parasites. Logistic regression models explored the relationship between IBS and parasite infection. The overall IBS prevalence among participants was 13.2% (9.3% males, 15.9% females). There was no difference in parasite carriage between IBS cases and controls, 16.6% versus 15.4% (P=0.78), nor among IBS subtypes. The pathophysiology of post-infectious IBS may be altered in the developing world as compared to industrialized nations and warrants investigation. |
| format | Article |
| id | doaj-art-10cc4bdcfb6847edb8e72ed9095f9f1c |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-10cc4bdcfb6847edb8e72ed9095f9f1c2025-08-20T03:55:45ZengWileyGastroenterology Research and Practice1687-61211687-630X2012-01-01201210.1155/2012/343812343812Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation EnvironmentDouglas R. Morgan0Matthew Benshoff1Mercedes Cáceres2Sylvia Becker-Dreps3Loreto Cortes4Christopher F. Martin5Max Schmulson6Rodolfo Peña7Division of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, Bioinformatics Building, Suite 4143, 130 Mason Farm Road, Chapel Hill, NC 27599-7080, USADivision of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, Bioinformatics Building, Suite 4143, 130 Mason Farm Road, Chapel Hill, NC 27599-7080, USASchool of Medicine, Universidad Nacional Autónoma de Nicaragua (UNAN), León, NicaraguaDivision of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, Bioinformatics Building, Suite 4143, 130 Mason Farm Road, Chapel Hill, NC 27599-7080, USASchool of Medicine, Universidad Nacional Autónoma de Nicaragua (UNAN), León, NicaraguaDivision of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, Bioinformatics Building, Suite 4143, 130 Mason Farm Road, Chapel Hill, NC 27599-7080, USASchool of Medicine, Universidad Nacional Autónoma de México (UNAM), Hospital General de México, Mexico City, DF, MexicoCentro de Intervención e Intervenciones en Salud, León, NicaraguaPostinfectious IBS is defined in the industrialized world as IBS onset following a sentinel gastrointestinal infection. In developing nations, where repeated bacterial and parasitic gastrointestinal infections are common, the IBS pathophysiology may be altered. Our aim was to investigate the relationship between intestinal parasite infection and IBS in the “nonsterile” developing world environment. IBS subjects were identified from a population-based sample of 1624 participants using the Rome II Modular Questionnaire. Stool samples from cases and randomly selected controls were examined for ova and parasites. Logistic regression models explored the relationship between IBS and parasite infection. The overall IBS prevalence among participants was 13.2% (9.3% males, 15.9% females). There was no difference in parasite carriage between IBS cases and controls, 16.6% versus 15.4% (P=0.78), nor among IBS subtypes. The pathophysiology of post-infectious IBS may be altered in the developing world as compared to industrialized nations and warrants investigation.http://dx.doi.org/10.1155/2012/343812 |
| spellingShingle | Douglas R. Morgan Matthew Benshoff Mercedes Cáceres Sylvia Becker-Dreps Loreto Cortes Christopher F. Martin Max Schmulson Rodolfo Peña Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment Gastroenterology Research and Practice |
| title | Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment |
| title_full | Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment |
| title_fullStr | Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment |
| title_full_unstemmed | Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment |
| title_short | Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment |
| title_sort | irritable bowel syndrome and gastrointestinal parasite infection in a developing nation environment |
| url | http://dx.doi.org/10.1155/2012/343812 |
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