Hepatic ferroptosis induced by Clonorchis sinensis exacerbates liver fibrosis.

Hepatic ferroptosis induced by Clonorchis sinensis exacerbates liver fibrosis.

Clonorchis sinensis (C. sinensis) is a food-borne zoonotic parasite link to liver fibrosis and cholangiocarcinoma. Limited understanding of its mechanisms in causing liver fibrosis has impeded therapeutic advances for C. sinensis-induced liver lesions. Ferroptosis, a novel form of cell death involvi...

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Bibliographic Details
Main Authors: Haoyang Zhang, Xiaocen Wang, Xu Zhang, Yeting Ma, Penglin Bao, Yanhui Yu, Yuru Wang, Pengtao Gong, Nan Zhang, Soon-Ok Lee, Xin Li, Jianhua Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0013164
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