A cross-tissue transcriptome-wide association study identifies WDPCP as a potential susceptibility gene for coronary atherosclerosis

A cross-tissue transcriptome-wide association study identifies WDPCP as a potential susceptibility gene for coronary atherosclerosis

Background: Coronary atherosclerosis (CAS) is a complex chronic inflammatory disease with significant genetic and environmental contributions. While genome-wide association studies (GWAS) have pinpointed many risk loci, over 75 % are in non-coding regions, complicating functional analysis and unders...

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Bibliographic Details
Main Authors: Xinyue Hu, Guanglei Chen, Xiaofang Yang, Jin Cui, Ning Zhang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Atherosclerosis Plus
Subjects:
Coronary atherosclerosis
Cross-tissue TWAS
UTMOST
FUSION
MAGMA
COJO
Online Access:http://www.sciencedirect.com/science/article/pii/S2667089524000506
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