Comparison of cervical cancer screening by visual inspection with acetic acid versus cervical-cytology in pregnancy
Aims: The aim of this study was to compare visual inspection with acetic acid (VIA) with cervical cytology for cervical cancer screening in pregnant women. Settings and Design: A prospective cohort study was conducted after institutional ethical committee approval in a tertiary care hospital in Nort...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2019-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2019;volume=40;issue=1;spage=85;epage=89;aulast= |
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| author | Saritha Shamsunder Deepika Pannu Geetika Khanna Ananya Banerjee Vijay Zutshi Sunita Malik |
| author_facet | Saritha Shamsunder Deepika Pannu Geetika Khanna Ananya Banerjee Vijay Zutshi Sunita Malik |
| author_sort | Saritha Shamsunder |
| collection | DOAJ |
| description | Aims: The aim of this study was to compare visual inspection with acetic acid (VIA) with cervical cytology for cervical cancer screening in pregnant women. Settings and Design: A prospective cohort study was conducted after institutional ethical committee approval in a tertiary care hospital in Northern India. Pregnant women of gestational age <28 weeks were randomly recruited from the antenatal clinic. Subjects and Methods: All eligible women had a Pap smear followed by VIA; colposcopy was performed if either test was positive. Swede score was used for grading of the acetowhite lesion; biopsy was planned if Swede score was ≥8. Statistical Analysis Used: The sensitivity, specificity, and predictive values for both screening methods were compared with colposcopy as the reference standard. Results: There were 370 low-risk pregnant women in the age group of 20–36 years in the study with a mean parity was 2.1, and the median period of gestation of 14.6 weeks. Abnormal Pap cytology was seen in 5.9% (n = 22) of patients; the abnormalities were ASCUS in 13 (59%), LSIL in 4 (18.2%), and AGC-NOS in 5 (22.7%) patients. VIA positivity was found in 8.4% (n = 31). The positive predictive value was 31.8% for cervical cytology and 48.4% for VIA (P = 0.001). No invasive lesion was detected. Positive predictive value of VIA was significantly higher than Pap cytology for detection of abnormal lesions. Conclusions: VIA is a cost-effective method with better predictive value than Pap smear for cervical cancer screening in pregnant women. |
| format | Article |
| id | doaj-art-10b0be8f4ca54a7e806ca62c8b8248d2 |
| institution | Kabale University |
| issn | 0971-5851 0975-2129 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-10b0be8f4ca54a7e806ca62c8b8248d22025-08-20T03:55:45ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292019-01-01401858910.4103/ijmpo.ijmpo_40_18Comparison of cervical cancer screening by visual inspection with acetic acid versus cervical-cytology in pregnancySaritha ShamsunderDeepika PannuGeetika KhannaAnanya BanerjeeVijay ZutshiSunita MalikAims: The aim of this study was to compare visual inspection with acetic acid (VIA) with cervical cytology for cervical cancer screening in pregnant women. Settings and Design: A prospective cohort study was conducted after institutional ethical committee approval in a tertiary care hospital in Northern India. Pregnant women of gestational age <28 weeks were randomly recruited from the antenatal clinic. Subjects and Methods: All eligible women had a Pap smear followed by VIA; colposcopy was performed if either test was positive. Swede score was used for grading of the acetowhite lesion; biopsy was planned if Swede score was ≥8. Statistical Analysis Used: The sensitivity, specificity, and predictive values for both screening methods were compared with colposcopy as the reference standard. Results: There were 370 low-risk pregnant women in the age group of 20–36 years in the study with a mean parity was 2.1, and the median period of gestation of 14.6 weeks. Abnormal Pap cytology was seen in 5.9% (n = 22) of patients; the abnormalities were ASCUS in 13 (59%), LSIL in 4 (18.2%), and AGC-NOS in 5 (22.7%) patients. VIA positivity was found in 8.4% (n = 31). The positive predictive value was 31.8% for cervical cytology and 48.4% for VIA (P = 0.001). No invasive lesion was detected. Positive predictive value of VIA was significantly higher than Pap cytology for detection of abnormal lesions. Conclusions: VIA is a cost-effective method with better predictive value than Pap smear for cervical cancer screening in pregnant women.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2019;volume=40;issue=1;spage=85;epage=89;aulast=Cervical cancer screeningcervical cytologypregnancyvisual inspection with acetic acid |
| spellingShingle | Saritha Shamsunder Deepika Pannu Geetika Khanna Ananya Banerjee Vijay Zutshi Sunita Malik Comparison of cervical cancer screening by visual inspection with acetic acid versus cervical-cytology in pregnancy Indian Journal of Medical and Paediatric Oncology Cervical cancer screening cervical cytology pregnancy visual inspection with acetic acid |
| title | Comparison of cervical cancer screening by visual inspection with acetic acid versus cervical-cytology in pregnancy |
| title_full | Comparison of cervical cancer screening by visual inspection with acetic acid versus cervical-cytology in pregnancy |
| title_fullStr | Comparison of cervical cancer screening by visual inspection with acetic acid versus cervical-cytology in pregnancy |
| title_full_unstemmed | Comparison of cervical cancer screening by visual inspection with acetic acid versus cervical-cytology in pregnancy |
| title_short | Comparison of cervical cancer screening by visual inspection with acetic acid versus cervical-cytology in pregnancy |
| title_sort | comparison of cervical cancer screening by visual inspection with acetic acid versus cervical cytology in pregnancy |
| topic | Cervical cancer screening cervical cytology pregnancy visual inspection with acetic acid |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2019;volume=40;issue=1;spage=85;epage=89;aulast= |
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