Infective endocarditis of a rare etiology: Serratia marcescens

Infective endocarditis (IE) is a unique diagnostic and therapeutic challenge. It is a severe disease, fatal before penicillin discovery. Atypical presentations frequently led to delayed diagnosis and poor outcome. There was little information about the natural history of the vegetations during medic...

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Main Authors: Đokić Milomir, Milanović Milomir, Begović Vesna, Ristić-Anđelkov Anđelka, Tomanović Branka
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2004-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2004/0042-84500406689D.pdf
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author Đokić Milomir
Milanović Milomir
Begović Vesna
Ristić-Anđelkov Anđelka
Tomanović Branka
author_facet Đokić Milomir
Milanović Milomir
Begović Vesna
Ristić-Anđelkov Anđelka
Tomanović Branka
author_sort Đokić Milomir
collection DOAJ
description Infective endocarditis (IE) is a unique diagnostic and therapeutic challenge. It is a severe disease, fatal before penicillin discovery. Atypical presentations frequently led to delayed diagnosis and poor outcome. There was little information about the natural history of the vegetations during medical treatment or the relation of morphologic changes in vegetation to late complications. Application of a new diagnostic criteria and echocardiography, increased the number of definite diagnosis. Trans-thoracic and trans-esophageal echocardiography had an established role in the management of patients with IE. The evolution of vegetation size, its mobility, and consistency, the extent of the disease, and the severity of valvular regurgutation were related to late complications. With therapeutic options including modern antibiotic treatment and early surgical intervention IE turned out to be a curable disease. Reduction in mortality also depended on prevention. Antibiotic prophylaxis of IE was important, but low mortality was also the result of early treatment, especially in the event of early recognition of symptoms and signs of the disease.
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issn 0042-8450
language English
publishDate 2004-01-01
publisher Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
record_format Article
series Vojnosanitetski Pregled
spelling doaj-art-109d40cda42f48bba77c39a58ccbffe82025-08-20T02:02:20ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502004-01-0161668969410.2298/VSP0406689DInfective endocarditis of a rare etiology: Serratia marcescensĐokić MilomirMilanović MilomirBegović VesnaRistić-Anđelkov AnđelkaTomanović BrankaInfective endocarditis (IE) is a unique diagnostic and therapeutic challenge. It is a severe disease, fatal before penicillin discovery. Atypical presentations frequently led to delayed diagnosis and poor outcome. There was little information about the natural history of the vegetations during medical treatment or the relation of morphologic changes in vegetation to late complications. Application of a new diagnostic criteria and echocardiography, increased the number of definite diagnosis. Trans-thoracic and trans-esophageal echocardiography had an established role in the management of patients with IE. The evolution of vegetation size, its mobility, and consistency, the extent of the disease, and the severity of valvular regurgutation were related to late complications. With therapeutic options including modern antibiotic treatment and early surgical intervention IE turned out to be a curable disease. Reduction in mortality also depended on prevention. Antibiotic prophylaxis of IE was important, but low mortality was also the result of early treatment, especially in the event of early recognition of symptoms and signs of the disease.http://www.doiserbia.nb.rs/img/doi/0042-8450/2004/0042-84500406689D.pdfendocarditisbacterialheart valve diseasesmitral valveserratia marcescensanti-bacterial agentsprognosistreatment outcome
spellingShingle Đokić Milomir
Milanović Milomir
Begović Vesna
Ristić-Anđelkov Anđelka
Tomanović Branka
Infective endocarditis of a rare etiology: Serratia marcescens
Vojnosanitetski Pregled
endocarditis
bacterial
heart valve diseases
mitral valve
serratia marcescens
anti-bacterial agents
prognosis
treatment outcome
title Infective endocarditis of a rare etiology: Serratia marcescens
title_full Infective endocarditis of a rare etiology: Serratia marcescens
title_fullStr Infective endocarditis of a rare etiology: Serratia marcescens
title_full_unstemmed Infective endocarditis of a rare etiology: Serratia marcescens
title_short Infective endocarditis of a rare etiology: Serratia marcescens
title_sort infective endocarditis of a rare etiology serratia marcescens
topic endocarditis
bacterial
heart valve diseases
mitral valve
serratia marcescens
anti-bacterial agents
prognosis
treatment outcome
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2004/0042-84500406689D.pdf
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AT milanovicmilomir infectiveendocarditisofarareetiologyserratiamarcescens
AT begovicvesna infectiveendocarditisofarareetiologyserratiamarcescens
AT risticanđelkovanđelka infectiveendocarditisofarareetiologyserratiamarcescens
AT tomanovicbranka infectiveendocarditisofarareetiologyserratiamarcescens