Giant nodular hidradenoma of the thigh: a case report highlighting cytological pitfalls
Abstract Nodular hidradenoma is a rare eccrine adnexal tumour that can arise in various locations, typically presenting as a solitary, slow-growing, well-circumscribed, firm, and non-tender dermal lesion. It may show discolouration, ulceration, or serous discharge, mimicking metastatic tumours, carc...
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| Language: | English |
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BMC
2025-07-01
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| Series: | Surgical and Experimental Pathology |
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| Online Access: | https://doi.org/10.1186/s42047-025-00195-3 |
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| author | Bhagyashree Bhagyashree Priyamvada Singhal Sakshi Goyal Rituraj Rituraj Usha Joshi |
| author_facet | Bhagyashree Bhagyashree Priyamvada Singhal Sakshi Goyal Rituraj Rituraj Usha Joshi |
| author_sort | Bhagyashree Bhagyashree |
| collection | DOAJ |
| description | Abstract Nodular hidradenoma is a rare eccrine adnexal tumour that can arise in various locations, typically presenting as a solitary, slow-growing, well-circumscribed, firm, and non-tender dermal lesion. It may show discolouration, ulceration, or serous discharge, mimicking metastatic tumours, carcinoma, or sarcoma. Due to its atypical presentation and lack of definitive radiological criteria, histopathology is the gold standard for diagnosis. While its subcutaneous location makes it suitable for fine needle aspiration cytology (FNAC), this technique is rarely used for small lesions, leading to limited cytomorphological data. FNAC is a cost-effective, quick, and simple tool, particularly useful in complex cases for preoperative diagnosis. Accurate identification is essential to avoid unnecessary radical treatment. This case report highlights the importance of considering nodular hidradenoma as a differential diagnosis when evaluating FNAC samples from nodular lesions in the subcutaneous region, regardless of their size or location. |
| format | Article |
| id | doaj-art-108b70bd3d904db39c3e8df6bb8118ce |
| institution | Kabale University |
| issn | 2520-8454 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Surgical and Experimental Pathology |
| spelling | doaj-art-108b70bd3d904db39c3e8df6bb8118ce2025-08-20T04:01:56ZengBMCSurgical and Experimental Pathology2520-84542025-07-01811410.1186/s42047-025-00195-3Giant nodular hidradenoma of the thigh: a case report highlighting cytological pitfallsBhagyashree Bhagyashree0Priyamvada Singhal1Sakshi Goyal2Rituraj Rituraj3Usha Joshi4Department of Pathology, GMC HaldwaniDepartment of Pathology, GMC HaldwaniDepartment of Pathology, GMC HaldwaniDepartment of Pathology, GMC HaldwaniDepartment of Pathology, GMC HaldwaniAbstract Nodular hidradenoma is a rare eccrine adnexal tumour that can arise in various locations, typically presenting as a solitary, slow-growing, well-circumscribed, firm, and non-tender dermal lesion. It may show discolouration, ulceration, or serous discharge, mimicking metastatic tumours, carcinoma, or sarcoma. Due to its atypical presentation and lack of definitive radiological criteria, histopathology is the gold standard for diagnosis. While its subcutaneous location makes it suitable for fine needle aspiration cytology (FNAC), this technique is rarely used for small lesions, leading to limited cytomorphological data. FNAC is a cost-effective, quick, and simple tool, particularly useful in complex cases for preoperative diagnosis. Accurate identification is essential to avoid unnecessary radical treatment. This case report highlights the importance of considering nodular hidradenoma as a differential diagnosis when evaluating FNAC samples from nodular lesions in the subcutaneous region, regardless of their size or location.https://doi.org/10.1186/s42047-025-00195-3Adenexal tumoursNodular hidradenomaSarcomaCytomorphologySubcutaneous mass |
| spellingShingle | Bhagyashree Bhagyashree Priyamvada Singhal Sakshi Goyal Rituraj Rituraj Usha Joshi Giant nodular hidradenoma of the thigh: a case report highlighting cytological pitfalls Surgical and Experimental Pathology Adenexal tumours Nodular hidradenoma Sarcoma Cytomorphology Subcutaneous mass |
| title | Giant nodular hidradenoma of the thigh: a case report highlighting cytological pitfalls |
| title_full | Giant nodular hidradenoma of the thigh: a case report highlighting cytological pitfalls |
| title_fullStr | Giant nodular hidradenoma of the thigh: a case report highlighting cytological pitfalls |
| title_full_unstemmed | Giant nodular hidradenoma of the thigh: a case report highlighting cytological pitfalls |
| title_short | Giant nodular hidradenoma of the thigh: a case report highlighting cytological pitfalls |
| title_sort | giant nodular hidradenoma of the thigh a case report highlighting cytological pitfalls |
| topic | Adenexal tumours Nodular hidradenoma Sarcoma Cytomorphology Subcutaneous mass |
| url | https://doi.org/10.1186/s42047-025-00195-3 |
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