Template-associated crystallization of organically modified CaCO3 via dual-membrane double migration technique: impact of voltage and temperature
Abstract Calcium Carbonate (CaCO3) is of great interest when considering it as a biomaterial or biomaterial additive due to its high capability to release calcium ions. It is interesting to explore the synthesis of template-associated CaCO3 using a biomimetic approach to facilitate its use in tissue...
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| Format: | Article |
| Language: | English |
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Springer
2025-07-01
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| Series: | Discover Materials |
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| Online Access: | https://doi.org/10.1007/s43939-025-00335-2 |
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| author | Salman Muhammad Ilyas Sadia Zakir Jangda Hans-Peter Wiesmann Benjamin Kruppke |
| author_facet | Salman Muhammad Ilyas Sadia Zakir Jangda Hans-Peter Wiesmann Benjamin Kruppke |
| author_sort | Salman Muhammad Ilyas |
| collection | DOAJ |
| description | Abstract Calcium Carbonate (CaCO3) is of great interest when considering it as a biomaterial or biomaterial additive due to its high capability to release calcium ions. It is interesting to explore the synthesis of template-associated CaCO3 using a biomimetic approach to facilitate its use in tissue-engineered scaffolds that follow biological models. For this reason, we designed a setup for the growth of CaCO3 crystals on an organic template molecule, denatured collagen (gelatin). The experiments used a modified double migration technique designed to facilitate ion migration within the template molecule as a gel barrier (layer). The setup involved two reservoirs where ions were guided into the gelatin layer under the influence of an applied voltage. The process was further optimized by systematically varying both the temperature and applied voltage. Within the layer, the ions undergo mineralization, resulting in the formation of CaCO3 polymorphs. The findings indicate that the process of CaCO3 mineralization on organic template molecules was significantly influenced by temperature and voltage. The optimal conditions for CaCO3 formation were achieved under influence of voltage at 1 V. The selected temperatures for the mineralization were 4 ⁰C, 20 °C (room temperature), and 50 °C. It was found that low temperatures favour calcite formation, while at 50 °C, all three polymorphs, calcite, vaterite, and aragonite, were observed. This shows that controlled temperature and voltage-driven ion migration can be employed to tailor the crystallization of CaCO3 in the presence of the organic template molecule, enabling the synthesis of biomimetic minerals. |
| format | Article |
| id | doaj-art-1085e33bbba34f99b6d7ac6dcb8aa42e |
| institution | DOAJ |
| issn | 2730-7727 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Materials |
| spelling | doaj-art-1085e33bbba34f99b6d7ac6dcb8aa42e2025-08-20T03:06:39ZengSpringerDiscover Materials2730-77272025-07-015111910.1007/s43939-025-00335-2Template-associated crystallization of organically modified CaCO3 via dual-membrane double migration technique: impact of voltage and temperatureSalman Muhammad Ilyas0Sadia Zakir Jangda1Hans-Peter Wiesmann2Benjamin Kruppke3Institute of Materials Science, Technische Universität DresdenInstitute of Materials Science, Technische Universität DresdenInstitute of Materials Science, Technische Universität DresdenInstitute of Materials Science, Technische Universität DresdenAbstract Calcium Carbonate (CaCO3) is of great interest when considering it as a biomaterial or biomaterial additive due to its high capability to release calcium ions. It is interesting to explore the synthesis of template-associated CaCO3 using a biomimetic approach to facilitate its use in tissue-engineered scaffolds that follow biological models. For this reason, we designed a setup for the growth of CaCO3 crystals on an organic template molecule, denatured collagen (gelatin). The experiments used a modified double migration technique designed to facilitate ion migration within the template molecule as a gel barrier (layer). The setup involved two reservoirs where ions were guided into the gelatin layer under the influence of an applied voltage. The process was further optimized by systematically varying both the temperature and applied voltage. Within the layer, the ions undergo mineralization, resulting in the formation of CaCO3 polymorphs. The findings indicate that the process of CaCO3 mineralization on organic template molecules was significantly influenced by temperature and voltage. The optimal conditions for CaCO3 formation were achieved under influence of voltage at 1 V. The selected temperatures for the mineralization were 4 ⁰C, 20 °C (room temperature), and 50 °C. It was found that low temperatures favour calcite formation, while at 50 °C, all three polymorphs, calcite, vaterite, and aragonite, were observed. This shows that controlled temperature and voltage-driven ion migration can be employed to tailor the crystallization of CaCO3 in the presence of the organic template molecule, enabling the synthesis of biomimetic minerals.https://doi.org/10.1007/s43939-025-00335-2BiomineralizationBiomimetic approachDouble diffusionCalcium carbonateGelatin |
| spellingShingle | Salman Muhammad Ilyas Sadia Zakir Jangda Hans-Peter Wiesmann Benjamin Kruppke Template-associated crystallization of organically modified CaCO3 via dual-membrane double migration technique: impact of voltage and temperature Discover Materials Biomineralization Biomimetic approach Double diffusion Calcium carbonate Gelatin |
| title | Template-associated crystallization of organically modified CaCO3 via dual-membrane double migration technique: impact of voltage and temperature |
| title_full | Template-associated crystallization of organically modified CaCO3 via dual-membrane double migration technique: impact of voltage and temperature |
| title_fullStr | Template-associated crystallization of organically modified CaCO3 via dual-membrane double migration technique: impact of voltage and temperature |
| title_full_unstemmed | Template-associated crystallization of organically modified CaCO3 via dual-membrane double migration technique: impact of voltage and temperature |
| title_short | Template-associated crystallization of organically modified CaCO3 via dual-membrane double migration technique: impact of voltage and temperature |
| title_sort | template associated crystallization of organically modified caco3 via dual membrane double migration technique impact of voltage and temperature |
| topic | Biomineralization Biomimetic approach Double diffusion Calcium carbonate Gelatin |
| url | https://doi.org/10.1007/s43939-025-00335-2 |
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