Extracellular vesicles in dairy cattle: research progress and prospects for practical applications
Abstract Intensive dairying has diminished infectious disease resistance in dairy cattle and increased the risk of disorders affecting milk quality and productive life. Development of novel health monitoring technologies, optimization of disease treatment protocols using novel biomarkers, and develo...
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| Format: | Article |
| Language: | English |
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BMC
2025-08-01
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| Series: | Journal of Animal Science and Biotechnology |
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| Online Access: | https://doi.org/10.1186/s40104-025-01242-5 |
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| author | Nan Wang Boqi Zhang Juan J. Loor Chunjin Li Xu Zhou |
| author_facet | Nan Wang Boqi Zhang Juan J. Loor Chunjin Li Xu Zhou |
| author_sort | Nan Wang |
| collection | DOAJ |
| description | Abstract Intensive dairying has diminished infectious disease resistance in dairy cattle and increased the risk of disorders affecting milk quality and productive life. Development of novel health monitoring technologies, optimization of disease treatment protocols using novel biomarkers, and development of antibiotic substitutes are necessary to further enhance the productivity of dairy cattle. Extracellular vesicles (EVs) are key mediators of cellular communication and are essential for maintaining intracellular homeostasis and regulating various physiological and pathological processes. Establishing a network of mechanisms by which EVs regulate physiological processes in dairy cattle will contribute to the development of new technologies for early disease diagnosis and disease treatment. This review summarizes the molecular characterization and advances in the study of EVs in dairy cattle and focuses on the reported mechanisms of action. Prospects and limitations for the application of EVs in monitoring health status, disease treatment and assisted reproduction are discussed. |
| format | Article |
| id | doaj-art-107c97f1c96f4bee9dab0dca9323d7af |
| institution | Kabale University |
| issn | 2049-1891 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Animal Science and Biotechnology |
| spelling | doaj-art-107c97f1c96f4bee9dab0dca9323d7af2025-08-20T03:43:10ZengBMCJournal of Animal Science and Biotechnology2049-18912025-08-0116112210.1186/s40104-025-01242-5Extracellular vesicles in dairy cattle: research progress and prospects for practical applicationsNan Wang0Boqi Zhang1Juan J. Loor2Chunjin Li3Xu Zhou4College of Animal Sciences, Jilin UniversityCollege of Animal Sciences, Jilin UniversityDepartment of Animal Sciences and Division of Nutritional Sciences, University of IllinoisCollege of Animal Sciences, Jilin UniversityCollege of Animal Sciences, Jilin UniversityAbstract Intensive dairying has diminished infectious disease resistance in dairy cattle and increased the risk of disorders affecting milk quality and productive life. Development of novel health monitoring technologies, optimization of disease treatment protocols using novel biomarkers, and development of antibiotic substitutes are necessary to further enhance the productivity of dairy cattle. Extracellular vesicles (EVs) are key mediators of cellular communication and are essential for maintaining intracellular homeostasis and regulating various physiological and pathological processes. Establishing a network of mechanisms by which EVs regulate physiological processes in dairy cattle will contribute to the development of new technologies for early disease diagnosis and disease treatment. This review summarizes the molecular characterization and advances in the study of EVs in dairy cattle and focuses on the reported mechanisms of action. Prospects and limitations for the application of EVs in monitoring health status, disease treatment and assisted reproduction are discussed.https://doi.org/10.1186/s40104-025-01242-5Extracellular vesiclesGastrointestinal tractImmunityMastitisMetabolism |
| spellingShingle | Nan Wang Boqi Zhang Juan J. Loor Chunjin Li Xu Zhou Extracellular vesicles in dairy cattle: research progress and prospects for practical applications Journal of Animal Science and Biotechnology Extracellular vesicles Gastrointestinal tract Immunity Mastitis Metabolism |
| title | Extracellular vesicles in dairy cattle: research progress and prospects for practical applications |
| title_full | Extracellular vesicles in dairy cattle: research progress and prospects for practical applications |
| title_fullStr | Extracellular vesicles in dairy cattle: research progress and prospects for practical applications |
| title_full_unstemmed | Extracellular vesicles in dairy cattle: research progress and prospects for practical applications |
| title_short | Extracellular vesicles in dairy cattle: research progress and prospects for practical applications |
| title_sort | extracellular vesicles in dairy cattle research progress and prospects for practical applications |
| topic | Extracellular vesicles Gastrointestinal tract Immunity Mastitis Metabolism |
| url | https://doi.org/10.1186/s40104-025-01242-5 |
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