Effect of Solvents on the Fluorescent Spectroscopy of BODIPY-520 Derivative
Photodynamic therapy (PDT) is a selective and minimally invasive technique for the treatment of tumors. It includes three components such as photosensitizer, light, and molecular oxygen. The purpose of this work is to investigate the effect of the solvents such as methanol, ethanol, acetone, and wat...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Spectroscopy |
| Online Access: | http://dx.doi.org/10.1155/2022/1172183 |
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| author | Buthaina Kamel Moustafa Sayem El-Daher Wesam Bachir Amina Ibrahim Sinan Aljalali |
| author_facet | Buthaina Kamel Moustafa Sayem El-Daher Wesam Bachir Amina Ibrahim Sinan Aljalali |
| author_sort | Buthaina Kamel |
| collection | DOAJ |
| description | Photodynamic therapy (PDT) is a selective and minimally invasive technique for the treatment of tumors. It includes three components such as photosensitizer, light, and molecular oxygen. The purpose of this work is to investigate the effect of the solvents such as methanol, ethanol, acetone, and water on fluorescent spectroscopy produced by one of the BODIPY derivatives in turbid media. A 520 nm laser diode is used for exciting one of the BODIPY derivatives as a photosensitizer in tissue-like optical phantoms. Results show that the photosensitizer studied without absorption and scattering components in the methanol and ethanol solvent has a prominent fluorescence peak at 600 nm, whereas acetone solvent has a prominent fluorescence peak at 546 nm. Experimental results reveal that when absorption and scattering components are present in addition to the studied solvents, the characteristic fluorescence intensity peak is red-shifted to 678 nm. |
| format | Article |
| id | doaj-art-106c0f0bb5034e2ca1d4ba5719e64dd8 |
| institution | OA Journals |
| issn | 2314-4939 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Spectroscopy |
| spelling | doaj-art-106c0f0bb5034e2ca1d4ba5719e64dd82025-08-20T02:01:53ZengWileyJournal of Spectroscopy2314-49392022-01-01202210.1155/2022/1172183Effect of Solvents on the Fluorescent Spectroscopy of BODIPY-520 DerivativeButhaina Kamel0Moustafa Sayem El-Daher1Wesam Bachir2Amina Ibrahim3Sinan Aljalali4Biomedical Photonics LaboratoryLaser Spectroscopy LaboratoryBiomedical Photonics LaboratoryDepartment of ChemistryLaser Spectroscopy LaboratoryPhotodynamic therapy (PDT) is a selective and minimally invasive technique for the treatment of tumors. It includes three components such as photosensitizer, light, and molecular oxygen. The purpose of this work is to investigate the effect of the solvents such as methanol, ethanol, acetone, and water on fluorescent spectroscopy produced by one of the BODIPY derivatives in turbid media. A 520 nm laser diode is used for exciting one of the BODIPY derivatives as a photosensitizer in tissue-like optical phantoms. Results show that the photosensitizer studied without absorption and scattering components in the methanol and ethanol solvent has a prominent fluorescence peak at 600 nm, whereas acetone solvent has a prominent fluorescence peak at 546 nm. Experimental results reveal that when absorption and scattering components are present in addition to the studied solvents, the characteristic fluorescence intensity peak is red-shifted to 678 nm.http://dx.doi.org/10.1155/2022/1172183 |
| spellingShingle | Buthaina Kamel Moustafa Sayem El-Daher Wesam Bachir Amina Ibrahim Sinan Aljalali Effect of Solvents on the Fluorescent Spectroscopy of BODIPY-520 Derivative Journal of Spectroscopy |
| title | Effect of Solvents on the Fluorescent Spectroscopy of BODIPY-520 Derivative |
| title_full | Effect of Solvents on the Fluorescent Spectroscopy of BODIPY-520 Derivative |
| title_fullStr | Effect of Solvents on the Fluorescent Spectroscopy of BODIPY-520 Derivative |
| title_full_unstemmed | Effect of Solvents on the Fluorescent Spectroscopy of BODIPY-520 Derivative |
| title_short | Effect of Solvents on the Fluorescent Spectroscopy of BODIPY-520 Derivative |
| title_sort | effect of solvents on the fluorescent spectroscopy of bodipy 520 derivative |
| url | http://dx.doi.org/10.1155/2022/1172183 |
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